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首页> 外文期刊>Acta Radiologica >Infratentorial oligodendrogliomas: Imaging findings in six patients.
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Infratentorial oligodendrogliomas: Imaging findings in six patients.

机译：幕下少突神经胶质瘤：6例患者的影像学表现。

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BACKGROUND: Oligodendrogliomas are primarily supratentorial tumors. However, infrequently, they can also arise from infratentorial structures. There are only limited numbers of radiological articles on the specific imaging findings of this entity. PURPOSE: To investigate the imaging findings of infratentorial oligodendrogliomas. MATERIAL AND METHODS: We retrospectively reviewed the magnetic resonance imaging (MRI) findings and clinical records of six patients with pathologically proven infratentorial oligodendrogliomas between December 1994 and April 2008. Tumor location, circumscription, signal intensity (SI), enhancement pattern, the presence of restricted diffusion, and the change of the relative cerebral blood volume (rCBV) on MRI were evaluated. Results: In total, six patients (three male, three female; mean age 65 years, range 51-75 years) were included. The pathology revealed anaplastic oligodendrogliomas in all six patients. The location was cerebellum in four patients, medulla in one patient, and fourth ventricle and tegmentum in one patient. Three of them were of the infiltrative type, and the other three of the mass-forming type. The solid component of the tumors showed high SI (n=6) on FLAIR and T2-weighted images, and low (n=5) or iso (n=1) SI on T1-weighted images. All infiltrative lesions showed multifocal patchy enhancement, and mass-forming lesions showed heterogeneous enhancement (n=2) and diffuse homogeneous enhancement (n=1). Three patients had restricted diffusion, and one had leptomeningeal seeding. There was markedly increased rCBV on perfusion-weighted image (PWI) in one patient. Calcification or hemorrhage was not found. Tumor progression after operation, radiation therapy, gamma-knife surgery, or chemotherapy developed in five patients. CONCLUSION: Although infratentorial oligodendrogliomas did not show characteristic imaging findings, there was a tendency toward multifocal heterogeneous enhancement and absent or mild mass effect of infiltrative lesions. Infratentorial oligodendrogliomas may be more malignant than supratentorial oligodendrogliomas.
机译：背景：少突胶质细胞瘤主要是幕上肿瘤。但是，它们很少也可能来自于子午线结构。关于该实体特定影像学发现的放射学文章数量有限。目的：探讨影像学检查发现下颌少突神经胶质瘤。材料与方法：我们回顾性回顾了1994年12月至2008年4月间6例经病理证实的镜下少突神经胶质瘤患者的磁共振成像（MRI）结果和临床记录。肿瘤位置，限制，信号强度（SI），增强模式，限制扩散，并评估MRI的相对脑血容量（rCBV）的变化。结果：总共包括6例患者（男3例，女3例;平均年龄65岁，范围51-75岁）。病理显示所有6例患者均存在间变性少突胶质细胞瘤。该位置为四名患者的小脑，一名患者为髓质，一名患者为第四脑室和睑板。其中三个是浸润型，另外三个是成块型。肿瘤的固体成分在FLAIR和T2加权图像上显示高SI（n = 6），在T1加权图像上显示低（n = 5）或iso（n = 1）SI。所有浸润性病变均表现为多灶性斑块增强，肿块形成性病变均表现为异质性增强（n = 2）和弥散性均质增强（n = 1）。 3名患者扩散受限，1名有软脑膜播种。一名患者的灌注加权图像（PWI）的rCBV明显升高。未发现钙化或出血。五名患者在手术，放射疗法，伽玛刀手术或化学疗法后出现了肿瘤进展。结论：尽管腹膜下少突胶质细胞瘤没有表现出明显的影像学表现，但存在多灶性异质性增强和浸润性病变缺乏或轻度肿块的趋势。幕下少突神经胶质瘤可能比幕上少突神经胶质瘤更恶性。

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