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Study of Inflammatory Marker IL-6 and Sympathetic Activity Among WHR Matched Prehypertensive & Normotensive Males

机译:炎症标志物IL-6与匹配术前雄性雄性雄性雄性的交感神经活动

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Background: Evidence suggests that Prehypertension is an inflammatory process and cardiovascular damage due to the inflammation is initiated by sympathetic activity. Therefore this study was conducted with the objective to measure IL-6 and sympathetic function in Prehypertensive. Material and methods: A Case-control study was conducted on 40 prehypertensive (as per JNC VII criteria) male subjects between 20 to 40 years. Equal numbers of age and WHR matched normotensive males were taken for comparison. They were investigated for serum IL6 and sympathetic reactivity by sustained hand grip (SHG) test. Results: SerumlL-6 level was higher in prehypertensive than in normotensive, though insignificantly (p=0.17). Significantly higher resting heart rate (RHR) (p=.001) and significantly lower change in diastolic blood pressure (A DBP, p=0.000) following SHG test were observed in prehypertensive. No significant association was observed between IL-6 and ADBP in Prehypertensive.
机译:背景:证据表明,由于交感神经活性,急性疗法是炎症过程和由于炎症引起的心血管损伤。 因此,该研究是以衡量预血压性的IL-6和交感神经功能的目标。 材料和方法:在20至40岁之间进行40例预衰退(根据JNC VII标准)进行病例对照研究。 相同数量的年龄和WHR匹配的正常性雄性进行比较。 通过持续的手柄(SHG)试验研究了它们对血清IL6和交感神反应性。 结果:血清 - 6水平均高于正常循环,但不合理(P = 0.17)。 在Pre高血压中观察到SHG试验后,静息心率明显较高(P = .001)并显着降低SHG试验后的舒张压(DBP,P = 0.000)。 IL-6与Preputive的IL-6和ADBP之间没有显着关联。

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