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首页> 外文期刊>Indian journal of physiology and pharmacology >Aortic Pulse Wave Velocity is Associated with Functional Capacity in Young Healthy Individuals
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Aortic Pulse Wave Velocity is Associated with Functional Capacity in Young Healthy Individuals

机译：主动脉脉搏波速度与年轻健康个体的功能能力相关

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Introduction: Impaired functional capacity and aortic pulse wave velocity (PWV) are predictors of cardiovascular (CV) adverse outcomes in healthy individuals as well as in those with CV disease. However, interrelation between arterial PWV and functional capacity remain to be established. Hence, the aim of the present study was to assess the relationship between arterial PWV and functional capacity in young healthy individuals. Materials and methods: A cross-sectional study was conducted on young healthy subjects (n=58) with age ranging between 17-24 years. The PWV from four regions was included for the study: brachial-ankle PWV, carotid-PWV/aortic PWV, heart-brachial PWV and heart-ankle PWV. Functional capacity was evaluated using a six-minute walk test (6MWT). Relationship between variables were assessed using bivariate correlations and multiple linear regression analysis. Results: Walking-distance was significantly correlated with age (r=0.334; p=0.010) and aortic-PWV (r=-0.259; p=0.049). Aortic PWV was robustly associated with 6MWD even after multiple adjustments with potential confounders using several models. Conclusions: Our findings suggest that aortic-PWV is an independent predictor of functional capacity in young healthy individuals. There was an inverse association of aortic-PWV with walking-distance, suggesting that higher the aortic PWV, lower is the functional capacity.
机译：介绍：功能容量受损，主动脉脉搏波速度（PWV）是健康个体的心血管（CV）不良结果的预测因子，以及具有CV疾病的人。但是，仍有仍有待建立动脉PWV和功能能力之间的相互关系。因此，本研究的目的是评估年轻健康个体动脉PWV和功能能力之间的关系。材料和方法：在17-24岁之间的年龄范围内对年轻健康受试者（n = 58）进行横截面研究。该研究包括来自四个地区的PWV：肱踝关节PWV，颈动脉PWV /主动脉PWV，心脏臂PWV和Heart-Ankle PWV。使用六分钟的步行测试（6MWT）评估功能容量。使用Bifariate相关性和多元线性回归分析评估变量之间的关系。结果：步行距离与年龄有明显相关（r = 0.334; p = 0.010）和主动脉PWV（r = -0.259; p = 0.049）。即使在使用多种型号的潜在混血器的多次调整之后，主动脉PWV也与6MWD稳健相关。结论：我们的研究结果表明主动脉PWV是年轻健康个体功能能力的独立预测因子。主动脉PWV与步行距离的反向关联，表明主动脉PWV越高，较低的是功能能力。

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