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首页> 外文期刊>Indian journal of physiology and pharmacology >Comparative Study of Heart Rate Variability (HRV) in Major Depressive Disorder (MDD) & Healthy Individuals
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Comparative Study of Heart Rate Variability (HRV) in Major Depressive Disorder (MDD) & Healthy Individuals

机译：重症抑郁症（MDD）和健康个体心率变异性（HRV）的比较研究

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The present study was carried out to compare HRV between 50 newly diagnosed MDD patients & 50 age & sex matched controls. The purpose of this study is to understand the interplay between autonomic nervous system (ANS) and cardiovascular system (CVS) in the patients of MDD. ECG was recorded for 5 minutes on MEDICAID STUDENTS PHYSIOPAC in lead II in supine position after 30 minutes of relaxation. HRV was analyzed by using Kubios version 2.1 software. Resting heart rate was significantly increased in MDD patients. There was significant decrease in time domain indices of HRV i.e. SDNN, RMSSD, NN50 , PNN50. Low frequency (LF) was significantly increased (p<0.05) while high frequency (HF) was found to be significantly decreased in cases compared to controls. LF/HF ratio was increased in cases MDD patients have higher resting heart rate and decreased HRV suggestive of decreased parasympathetic activity as compared to controls pointing towards cardiac autonomic modulation.
机译：本研究进行了比较HRV在50例新诊断的MDD患者和50岁和性匹配对照中进行比较。 本研究的目的是了解MDD患者自主神经系统（ANS）和心血管系统（CVS）之间的相互作用。 在30分钟放松后，在仰卧位的Medicaid学生Physiopac的Medicaid学生Physiopac录制了5分钟。 使用Kubios版本2.1软件分析了HRV。 MDD患者休息心率显着增加。 HRV的时域指数显着降低，SDNN，RMSD，NN50，PNN50。 低频（LF）显着增加（P <0.05），而在与对照相比，发现在病例中发现高频（HF）显着降低。 在MDD患者具有较高的休息心率和降低的HRV方面，LF / HF比例增加，与指向心脏自主调制的对照相比，对副交感神经活性降低的提示。

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