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首页> 外文期刊>Acta Radiologica >Perfusion magnetic resonance imaging characteristics of intracerebral tuberculomas and its role in differentiating tuberculomas from metastases.
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Perfusion magnetic resonance imaging characteristics of intracerebral tuberculomas and its role in differentiating tuberculomas from metastases.

机译：脑结核的灌注磁共振成像特征及其在区分转移性结核中的作用。

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Intracerebral tuberculomas usually manifest as ring-enhancing of nodular lesions on magnetic resonance imaging (MRI). These imaging findings are also observed in other lesions like metastases and toxoplasmosis.To study the MRI perfusion characteristics of tuberculomas and its potential role in their definitive diagnosis. MATERIAL AND MEthods: Thirty-four tuberculomas were evaluated by conventional and perfusion MRI. The relative cerebral blood volume (rCBV) values of the center, peripheral wall, and perilesional neuroparenchymal tissue were calculated using rCBV maps. Ten ring-enhancing metastases were similarly evaluated and rCBV values of their peripheral walls were calculated.Thirty-one of the 34 tuberculomas were ring-enhancing or conglomerate lesions and revealed hypoperfused centers with hyperperfused peripheral walls, with the mean rCBV ± SD being 0.42 ± 0.25 and 2.04 ± 0.61, respectively. Three nodular enhancing lesions showed predominantly homogenous hyperperfusion, with the mean rCBV measuring 2.96 ± 0.39 (mean ± SD). The perilesional neuroparenchyma was hypoperfused in both cases. The metastases revealed mean rCBV ratio of the peripheral wall to be 5.43 ± 2.1 (mean ± SD). Analysis of the values by ROC curve method revealed a cut-off value of ≥3.745 for differentiating ring-enhancing metastases from ring-enhancing tuberculomas.Perfusion MR is a useful tool for the assessment of tuberculomas and can help differentiate them from neoplasms like metastases. It also has a potential role in monitoring therapy and for early detection of drug resistance.
机译：脑结核通常表现为磁共振成像（MRI）上的结节性病变的环形增强。这些影像学发现还可以在转移灶和弓形虫病等其他病变中观察到。研究结核病的MRI灌注特征及其在明确诊断中的潜在作用。材料与方法：34例肺结核通过常规和灌注MRI进行评估。使用rCBV图计算​​中心，外周壁和病灶周围神经实质组织的相对脑血容量（rCBV）值。相似地评估了10个增强环的转移并计算了其外周壁的rCBV值.34个结核瘤中有31个是环增强或聚集性病变，并显示低灌注中心和高灌注外周壁，平均rCBV±SD为0.42±分别为0.25和2.04±0.61。三个结节性增强病变主要表现为均匀的高灌注，平均rCBV为2.96±0.39（平均值±SD）。在两种情况下，病灶周围神经实质均被灌注不足。转移显示外周壁的平均rCBV比为5.43±2.1（平均值±SD）。通过ROC曲线法对这些值进行分析后发现，区分环增强型转移灶与环增强型结核瘤的临界值≥3.745。灌注MR是评估结核瘤的有用工具，可帮助将其与肿瘤（如转移瘤）区分开。它还在监测治疗和早期发现耐药性方面具有潜在作用。

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