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首页> 外文期刊>Indian Journal of Poultry Science >In vivo effect of Andrographis panniculata nees and Morinda citrifolia on expression of toll-like receptors in indigenous Nicobari fowl
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In vivo effect of Andrographis panniculata nees and Morinda citrifolia on expression of toll-like receptors in indigenous Nicobari fowl

机译：Andrographis Panniculata Nees和Morinda Citrifolia对土着尼科米禽类中的收费者样受体表达的体内效果

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摘要

A study on the effect of feeding of Nicobari fowl breeders with Andrographis panniculata (Kalmegh) and Morinda citrifoli (Noni) and its subsequent effect on TLR (Toll like receptors) expression in post-hatch chicks was carried out. Two hundred seventbreeding Nicobari fowls were assigned to each of three dietary treatments namely, Tl: Control groups; T2: Kalmegh @ 3g per bird pe day; T3: Noni @ 10ml per bird per day. Chicks were hatched out from experimental groups and at 15 days of age, spleen samples wer collected from chicks through slaughter. Expression of TLR was quantified with Real-Time PCR (QPCR) and fold difference ii expression of different TLRs was analysed. Supplementation Kalmegh significantly improved the expression levels of TLR3, TLR4 TLR5, by 5.4, 9.7 and 1.6 times, respectively as compared to control; while noni supplementation up regulated the expression levels o respective TLRs by 2.9, 5.0 and 0.48 times. We concluded that in vivo exposure to bioactive components present in herbal plants uj regulated the expression of TLR4 and TLR5 in chicks that is responsive for their antiviral inducing property at gene level. Thereb) kalmegh and noni might be promising alternatives for antibiotic growth promoters.
机译：进行了玉米多巴毛犬育种者喂养尼古拉饲料（Kalmegh）和Morinda Citrifoli（Noni）的疗效研究及其随后对孵卵后雏鸡中TLR（损伤相似的受体）表达的影响。将两百份乳房梭鱼分配给三种膳食治疗中的每一个，即TL：对照组; T2：每只鸟的Kalmegh @ 3G; T3：每鸟每天10ml。从实验组中孵化出来，在15天的时候孵化，脾脏样本通过屠宰从小鸡收集。用实时PCR（QPCR）量化TLR的表达，分析不同TLR的折叠差异II表达。与对照相比，补充kalmegh显着改善了TLR3，TLR4 TLR5，5.4,9.7和1.6倍的表达水平;虽然NONI补充了将表达水平的表达水平调节为2.9,5.0和0.48倍。我们得出结论，在草药植物中存在的生物活性成分，UJ中的生物活性成分调节雏鸡中TLR4和TLR5的表达，该表达响应于基因水平的抗病毒诱导性质。其中）Kalmegh和Noni可能是抗生素生长促进剂的有希望的替代品。

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  • 来源
    《Indian Journal of Poultry Science》 |2017年第3期|共4页
  • 作者

    T. SUJATHA; J. SUNDER; T.R. KANNAKI; A. KUNDU;

  • 作者单位

    Division of Animal Science ICAR-Central Island Agricultural Research Institute Port Blair- 744105 (A&

    N Islands);

    Division of Animal Science ICAR-Central Island Agricultural Research Institute Port Blair- 744105 (A&

    N Islands);

    Directorates of Poultry Research Rajendranagar Hyderabad 500030 AP India;

    Division of Animal Science ICAR-Central Island Agricultural Research Institute Port Blair- 744105 (A&

    N Islands);

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 家禽;
  • 关键词

    Breeder feed; Herbal supplement; Kalmegh; Noni; TLRs expression; Chicks;

    机译：饲料;草药补充;kalmegh;noni;tlrs表达;小鸡;

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