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首页> 外文期刊>Indian medical journal >Primary Gonadotropin-releasing Hormone Agonist Therapy for Suspected Endometriosis: A Nonsurgical Approach to the Management of Chronic Pelvic Pain
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Primary Gonadotropin-releasing Hormone Agonist Therapy for Suspected Endometriosis: A Nonsurgical Approach to the Management of Chronic Pelvic Pain

机译：主要促性腺激素 - 释放激素激动剂治疗疑似子宫内膜异位症：慢性骨盆疼痛管理的非必要方法

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摘要

Chronic pelvic pain is a condition that affects one in seven women of reproductive age billion annually before factoring in the costs of diagnostic testing. At many medical centers, endometriosis is the most common single cause of chronic pelvic pain; other causes include intra-abdominal adhesions, chronic pelvic inflammatory disease, ovarian cysts, and adenomyosis. The current approach to diagnosis and treatment of chronic pelvic pain is a two-step approach, with medical history, physical examination, laboratory testing, and empiric therapy (nonsteroidal antiinflammatory drugs, oral contraceptives, and/ or antibiotics) comprising Step 1 and surgical diagnosis with laparoscopy as Step 2. At many centers, the most common diagnosis at the time of laparoscopy for chronic pelvic pain is endometriosis, typically minimal to mild disease that can be effectively treated with hormonal therapy. Therefore, a rational alternative approach is a 3-month empirical course of therapy with a gonadotropin-releasing hormone agonist before laparoscopy. The advantages of this approach are the high rate of pain relief in women, the possibility of avoiding an invasive procedure (laparoscopy), the ability to extend therapy, if pain is relieved, to the full 6-month therapeutic course of endometriosis, and a potentially lower cost relative to laparoscopy.
机译：慢性骨盆疼痛是在治疗诊断测试成本之前每年每年一次影响七个妇女的七名妇女的病症。在许多医疗中心，子宫内膜异位症是慢性骨盆疼痛最常见的单一原因;其他原因包括腹部粘连，慢性盆腔炎，卵巢囊肿和腺梗阻。目前诊断和治疗慢性骨盆疼痛的方法是一种两步的方法，具有医学史，体检，实验室检测和经验治疗（非甾体类抗炎药，口腔避孕药和/或抗生素），包括步骤1和手术诊断随着腹腔镜检查作为步骤2.在许多中心，慢性盆腔疼痛的腹腔镜检查时最常见的诊断是子宫内膜异位症，通常与激素治疗有效处理的轻度疾病。因此，理性替代方法是腹腔镜检查前的促性腺激素释放激素激动剂的3个月实验疗程。这种方法的优点是女性的疼痛缓解率高，可能避免侵入性手术（腹腔镜检查），延长治疗的能力，如果疼痛释放，到完整的6个月治疗剂的子宫内膜异位症，和一个相对于腹腔镜检查的可能性较低。

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  • 来源
    《Indian medical journal》 |2018年第6期|共3页
  • 作者

    Amrita;

  • 作者单位

    Patna Senior Resident (Obst &

    Gynac) UCMS &

    GTB Hospital Delhi;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 医药、卫生;
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