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首页> 外文期刊>Industrial and organizational psychology >Study of new cellulosic dressing with enhanced antibacterial performance grafted with a biopolymer of chitosan and myrrh polysaccharide extract
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Study of new cellulosic dressing with enhanced antibacterial performance grafted with a biopolymer of chitosan and myrrh polysaccharide extract

机译：用壳聚糖和MyRRH多糖提取物嫁接增强抗菌性能的新纤维素敷料研究

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The treatment of chronic wounds represents a major interest for public health both medically and economically. Hence the need for a modern wound dressing that actively promotes the physiological process specific to healing. In this perspective we have studied the development of a new dressing able to offer a serious contribution to the dilemma of the various chronic wounds. A dressing grafted with two natural polysaccharides known for their multiple biological effects, chitosan and a carbohydrate polymer extracted from Commiphora myrrha (CMP). We began by studying the grafting of the two natural biopolymers onto cellulose dressings, via a polyacrylic acid as a crosslinking agent. An optimization study, revealed the different grafting parameters, the polymer concentration as well as the heat-setting time and temperature. After, different characterization techniques were carried out in order to evaluate the effectiveness of our grafting. The swelling test revealed a hydrophilicity enhancement which increased with the degree of grafting, a desired property for effective dressings. Infrared characterization as well as thermogravimetric analysis (TGA and DTA) confirmed the binding mode and the permanence of our grafting. XRD and mechanical characterization showed no change in the crystallinity or in the original mechanical properties of the functionalized dressings. Morphological SEM study, confirmed the presence of our grafting as well as its mode of distribution. Finally, a bacteriological study conducted, showed a clear improvement of the antimicrobial behavior of cellulosic wound dressings functionalized by our combined natural biopolymers. (C) 2019 The Author(s). Published by Elsevier B.V. on behalf of King Saud University.
机译：慢性伤口的治疗代表了在医学和经济上的公共卫生的主要利益。因此，需要一种现代伤口敷料，积极促进对愈合特异的生理过程。在这种观点中，我们研究了一种能够为各种慢性伤口的困境提供严重贡献的新敷料的发展。一种敷料，其嫁接了两种以其多种生物效应，壳聚糖和从Commiphora myrrha（CMP）提取的碳水化合物聚合物而闻名的两种天然多糖。我们开始通过将两种天然生物聚合物的接枝到纤维素敷料中，通过聚丙烯酸作为交联剂。优化研究，揭示了不同的接枝参数，聚合物浓度以及热凝固时间和温度。之后，进行了不同的表征技术，以评估我们的嫁接的有效性。溶胀测试揭示了亲水性增强，随着嫁接程度而增加，有效敷料的所需性质增加。红外表征以及热重分析（TGA和DTA）证实了绑定模式和我们嫁接的持久性。 XRD和机械表征显示结晶度或在官能化敷料的原始机械性能下没有变化。形态学SEM学习，证实了我们的嫁接和其分布方式。最后，进行了一种细菌学研究，表明，通过我们的合并天然生物聚合物官能化的纤维素伤口敷料的抗微生物行为的清楚提高。 （c）2019年作者。 elsevier b.v出版。代表沙特大学国王。

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