首页> 外文期刊>Acta Radiologica >Expansion of radiofrequency ablation volume by saturated NaCl saline injection in the area of vaporization.
【24h】

Expansion of radiofrequency ablation volume by saturated NaCl saline injection in the area of vaporization.

机译:在汽化区域中通过饱和NaCl盐水注射扩大射频消融体积。

获取原文
获取原文并翻译 | 示例
           

摘要

BACKGROUND: Vaporization around the radiofrequency (RF) electrode after RF application (RFA) limits the RF ablation area. Purpose: To determine whether saturated saline injected into the area of vaporization after initial RFA extends ablation area after further RFA. MATERIAL AND METHODS: RFA was performed in 18 ex vivo porcine livers and four in vivo rabbit erector spinae muscles. An RF electrode was used to ablate an area with 40W of parallel current for 15 min. The ablation margin was determined using a thermocouple, and the radius of the ablated area was measured. After RF electrode removal, saturated saline was infused through a percutaneous ethanol injection needle into the site of the original RFA in 11 liver samples and two erector spinae muscles. Three minutes later, RFA was resumed for 15 min. The remaining seven control liver samples and two spinae muscles received RFA without saline injection. The radius of the final ablated area was then measured. RESULTS: In the ex vivo study, injection of saturated saline significantly decreased tissue impedance (87.7+/-9.4 to 51.1+/-9.7 Omega, P<0.0001), and increased the mean radius of the ablated area (15.9+/-3.0 to 25.0+/-3.6 mm, P<0.0001). These significant changes were not observed without injection of saturated saline. Similar trends were found in the in vivo study. CONCLUSION: Injection of saturated saline into the area of vaporization around the RF electrode, followed by additional RFA, caused concentric expansion of the final ablation area, facilitating more efficient tumor ablation.
机译:背景:射频(RF)施加(RFA)后,射频(RF)电极周围的蒸发限制了射频消融区域。目的:确定在最初的RFA之后注入到汽化区域的饱和盐水是否在进一步的RFA之后扩展了消融区域。材料与方法:RFA在18例离体猪肝脏和4例体内兔竖脊肌中进行。使用RF电极以40W的并联电流烧蚀区域15分钟。使用热电偶确定消融裕度,并测量消融区域的半径。移除射频电极后,将饱和盐水通过经皮乙醇注射针注入11个肝脏样本和两条直立脊柱肌肉中原始RFA的部位。三分钟后,RFA恢复了15分钟。其余七个对照肝样本和两个脊柱肌肉未注射生理盐水而接受了RFA。然后测量最终烧蚀区域的半径。结果:在离体研究中,注射饱和盐水可显着降低组织阻抗(87.7 +/- 9.4至51.1 +/- 9.7 Omega,P <0.0001),并增加消融区域的平均半径(15.9 +/- 3.0)至25.0 +/- 3.6 mm,P <0.0001)。如果不注入饱和盐水,则不会观察到这些显着变化。在体内研究中发现了类似的趋势。结论:向射频电极周围的汽化区域注入饱和盐水,再进行额外的射频消融,导致最终的消融区域同心扩展,从而促进了更有效的肿瘤消融。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号