...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>BJU international >The effect of microsurgical varicocelectomy on serum follicle stimulating hormone, testosterone and free testosterone levels in infertile men with varicocele.
【24h】

The effect of microsurgical varicocelectomy on serum follicle stimulating hormone, testosterone and free testosterone levels in infertile men with varicocele.

机译：精索静脉曲张切除术对不育精索静脉曲张患者血清卵泡刺激素，睾丸激素和游离睾丸激素水平的影响。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVES: To analyse the effects of varicocelectomy on serum follicle-stimulating hormone (FSH), testosterone and free testosterone levels, and to investigate the interrelationships between seminal and hormonal variables. PATIENTS AND METHODS: The records were retrospectively evaluated for 78 infertile patients who underwent microsurgical inguinal varicocelectomy, with documented serum FSH, testosterone, free testosterone levels, sperm concentration and sperm motility before and after surgery. Left and bilateral varicoceles were detected in 40 and 38 patients, respectively. In addition, serum hormonal values of 10 fertile men in whom physical examinations and Doppler ultrasonography revealed no evidence of varicocele were recorded and used as a control group. RESULTS: The mean (sd) serum FSH levels of all patients decreased from 15.21 (3.34) before surgery to 10.82 (2.93) mIU/mL afterward (P=0.01), and serum testosterone levels increased from 5.63 (1.40) to 8.37 (2.2) ng/mL (P=0.01), whereas free testosterone levels increased from 23.13 (3.19) to 32.83 (4.37) pg/mL (P<0.001). In contrast to the significant difference in sperm motility before and after surgery of all patients (P<0.01), the difference in sperm count was insignificant (P>0.05). Thirty-six patients with high serum FSH levels before surgery had significantly lower levels afterward (P=0.001). In this group, the sperm concentration and motility also increased, from 17.66 (4.35) to 20.76 (4.37) million/mL (P=0.05) and from 30.9 (4.4)% to 37.5 (4.34)%, respectively (P=0.01). In the remaining 42 patients who had normal preoperative serum FSH levels, there was a slight decrease after surgery (P=0.02). Their sperm concentration increased slightly (P=0. 04), and motility also increased (P=0.001). Sixty patients had a significantly higher testosterone level after surgery; in this group the sperm concentration and motility increased (P=0.01). CONCLUSION: Varicocelectomy promotes Sertoli and Leydig cell function. The significant increase in serum free testosterone level results in a significant improvement in sperm concentration and motility.
机译：目的：分析精索静脉曲张切除术对血清卵泡刺激素（FSH），睾丸激素和游离睾丸激素水平的影响，并探讨精液和激素变量之间的相互关系。方法回顾性分析78例行显微腹股沟静脉曲张切除术的不育患者的病历，并记录其术前和术后的血清FSH，睾丸激素，游离睾丸激素水平，精子浓度和精子活力。分别在40和38例患者中检测到左和双侧精索静脉曲张。另外，记录了10名可育男性的血清激素水平，其中体格检查和多普勒超声检查未发现精索静脉曲张的证据，并将其用作对照组。结果：所有患者的血清FSH平均（sd）从手术前的15.21（3.34）降低至术后的10.82（2.93）mIU / mL（P = 0.01），血清睾丸激素水平从5.63（1.40）增加至8.37（2.2） ng / mL（P = 0.01），而游离睾丸激素水平从23.13（3.19）pg / mL增加到32.83（4.37）pg / mL（P <0.001）。与所有患者术前和术后精子活动性的显着差异相比（P <0.01），精子数量的差异均无统计学意义（P> 0.05）。术前血清FSH水平高的36例患者术后血脂水平明显降低（P = 0.001）。在该组中，精子浓度和运动力也分别从17.66（4.35）增加到20.76（4.37）百万/ mL（P = 0.05）和从30.9（4.4）％增加到37.5（4.34）％（P = 0.01） 。其余42名术前血清FSH水平正常的患者，手术后略有下降（P = 0.02）。他们的精子浓度略有增加（P = 0。04），运动力也有所增加（P = 0.001）。 60例患者术后睾丸激素水平明显升高;在这个组中，精子浓度和运动性增加（P = 0.01）。结论：精索静脉曲张切除术可促进Sertoli和Leydig细胞功能。血清游离睾丸激素水平的显着提高导致精子浓度和运动能力显着改善。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号