...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International endodontic journal >Effectiveness and clinical implications of the use of topical antibiotics in regenerative endodontic procedures: a review
【24h】

Effectiveness and clinical implications of the use of topical antibiotics in regenerative endodontic procedures: a review

机译：局部抗生素在再生牙髓手术中使用的有效性和临床意义：综述

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Abstract Regenerative endodontic procedures ( REP s) are biologically based procedures planned to replace damaged tissues, including dentinee and root structures, as well as cells of the pulp–dentine complex. Effective sterilization of the root canal is essential in REP s, and antibiotics have been widely used to disinfect root canals. The aim of this paper was to review the scientific literature on (i) Effectiveness of antibiotics used in REP s against bacteria implicated in endodontic disease; (ii) Scientific evidence supporting the use of topical antibiotics in REP s; (iii) Clinical implications of the use of antibiotics in REP s and the possible side effects; (iv) Effect of antibiotics on dental pulp stem cells; and (v) Ongoing research on the use of antibiotics in REP s. Antibiotics used in REP s are effective against bacteria implicated in endodontic infections. Triple antibiotic pastes with minocycline attain complete disinfection of immature teeth with necrotic pulps, without affecting SCAP . Experimental studies carried out in dogs support the use of antibiotics in REP s. Clinical studies report high success rates of RET using antibiotics as intracanal dressings. However, tooth discolouration is an important side effect of the use of TAP . An antibiotic paste containing only metronidazole and ciprofloxacin could be a good alternative to the use of TAP . The use of antibiotic‐containing scaffolds or clindamycin‐modified triple antibiotic (metronidazole, ciprofloxacin and clindamycin) polymer could be a biologically safe antimicrobial drug delivery system in REP s.
机译：摘要再生牙髓手术（REP S）是基于生物学上基础的程序，以替换损伤组织，包括牙本质和根系结构，以及牙髓牙本质复合物的细胞。根管的有效灭菌是批量代表中必需的，并且抗生素已被广泛用于消毒根系。本文的目的是审查（i）抗生素的有效性对抗椎间型疾病的抗生素的有效性; （ii）支持使用局部抗生素的科学证据; （iii）抗生素在代表和可能的副作用中使用临床意义; （iv）抗生素对牙髓干细胞的影响; （v）持续研究在代表中使用抗生素。代表S中使用的抗生素对涉及牙髓感染的细菌有效。含有米诺环素的三重抗生素糊状物与坏死纸浆的未成熟牙齿的完全消毒，而不会影响湿度。在狗中进行的实验研究支持在代表中使用抗生素。临床研究报告使用抗生素作为骨膜敷料的高成功率。然而，牙齿变色是使用水龙头的重要副作用。仅含有甲硝唑和环丙沙星的抗生素糊剂可能是使用水龙头的良好替代方案。使用含抗生素的支架或克林霉素改性三重抗生素（甲硝唑，环氟苯胺嘧啶和Clindamycin）聚合物可以是代表的生物安全的抗微生物药物递送系统。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号