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首页> 外文期刊>International archives of allergy and immunology >An Analysis of Skin Prick Tests to Latex and Patch Tests to Rubber Additives and other Causative Factors among Dental Professionals and Students with Contact Dermatoses
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An Analysis of Skin Prick Tests to Latex and Patch Tests to Rubber Additives and other Causative Factors among Dental Professionals and Students with Contact Dermatoses

机译：对乳胶添加剂的皮肤刺痛试验及橡胶添加剂和其他造成因素的牙科专业人士和与接触皮肤的学生的造成因子分析

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Background: Dental workers often experience unwanted allergic and nonallergic skin reactions resulting in different contact dermatoses (e.g., contact urticaria, irritant and allergic contact dermatitis) that are often attributed to rubber gloves. Objective: To examine allergic and nonallergic contact dermatoses by different methods amongst dental professionals and dental students, more specifically, reactions to natural rubber latex (NRL), rubber additives, and other causative factors. Methods: In this cross-sectional study we surveyed a total of 444 subjects (dentists, assistants, technicians, and students); 200 agreed to be tested to latex by the standard skin prick test (SPT) and prick-by-prick test, of whom 107 were patch tested to rubber additives (mercapto mix, thiuram mix, carba mix, and N-isopropyl-N-phenyl-4-phenylenediamine [IPPD]). Results: Skin lesions appeared significantly more frequently with longer work experience (p = 0.002; V = 0.181), frequent glove changes (p 0.001; V = 0.310), and hand washing (p 0.001; V = 0.263), and in subjects with a history of allergies (atopic dermatitis, allergic rhinitis, allergic conjunctivitis, and others) (p 0.001; V = 0.183). Positive SPTs to latex occurred in 14/200 subjects (7%), of whom 5/14 subjects (35.7%) were also positive in prick-by-prick tests. Patch tests were positive in 5/104 subjects (4.8%) (mercapto mix 1%, thiuram mix 1.9%, and carba mix 1.9%). Conclusion: Only a small number of our subjects were allergic to latex (7%) or rubber additives (4.8%). Thus, self-reported contact dermatoses (during NRL product use) in dental professionals and students are not commonly caused by allergies to latex and rubber additives, as is often assumed, but by other factors.
机译：背景：牙科工人经常遇到不需要的过敏性和非过敏性皮肤反应，导致不同的接触皮肤（例如，接触荨麻疹，刺激性和过敏性接触皮炎），这些反应通常归因于橡胶手套。目的：通过不同方法在牙科专业人士和牙科学生中检查过敏性和非过敏性接触皮肤，更具体地说，对天然橡胶胶乳（NRL），橡胶添加剂和其他致病因素的反应。方法：在这个横断面研究中，我们共同调查了444名科目（牙医，助理，技术人员和学生）; 200经200同意通过标准皮肤刺（SPT）和PRICR-BY-PRICK试验进行测试，其中107个是橡胶添加剂（巯基混合物，硫仑混合物，卡巴混合物和N-异丙基-N-苯基-4-苯二胺[IPPD]）。结果：皮肤病变更频繁地呈现出较长的工作经验（P = 0.002; v = 0.181），频繁手套变化（P <0.001; v = 0.310），手工洗涤（P <0.001; v = 0.263），在具有过敏历史的主题（特应性皮炎，过敏性鼻炎，过敏性结膜炎等）（P <0.001; v = 0.183）。在14/200个受试者（7％）中发生乳胶的正面Spts发生在刺破试验中的5/14受试者（35.7％）也是阳性的。贴剂试验在5/104受试者（4.8％）（巯基混合物1％，硫酸混合物1.9％，Carba混合1.9％）。结论：只有少数受试者对乳胶（7％）或橡胶添加剂（4.8％）过敏。因此，牙科专业人士和学生中的自我报告的接触皮肤（在NRL产品中使用期间）通常是对乳胶和橡胶添加剂的过敏造成的，正如通常认为的那样，但是通过其他因素。

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