Oral treatment with enrofloxacin creates anti-inflammatory environment that supports induction of tolerogenic dendritic cells

Strzepa Anna; Marcinska Katarzyna; Majewska-Szczepanik Monika; Szczepanik Marian

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Oral treatment with enrofloxacin creates anti-inflammatory environment that supports induction of tolerogenic dendritic cells

机译：用瑞氧氟沙星的口服处理产生抗炎环境，支持诱导耐受性树突细胞的诱导

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Background: Oral enrofloxacin treatment altered the gut microbiome promoting anti-inflammatory bacteria. The dysbiosis promotes regulatory cell induction in the intestines and in the periphery, which suppresses contact sensitivity. Bacterial-derived signals promote regulatory cell induction both directly and indirectly by influencing the phenotype of dendritic cells (DC).

机译：背景：口腔富含氧化萘治疗改变肠道微生物组促进抗炎细菌。困难促进肠道和周边的调节细胞诱导，抑制接触敏感性。通过影响树突细胞（DC）的表型，细菌衍生信号直接和间接地促进调节细胞诱导。

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来源
《International immunopharmacology》 |2019年第2019期|共8页
作者
Strzepa Anna; Marcinska Katarzyna; Majewska-Szczepanik Monika; Szczepanik Marian;
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作者单位

Jagiellonian Univ Med Coll Fac Hlth Sci Dept Med Biol Ul Kopernika 7 PL-31034 Krakow Poland;

Jagiellonian Univ Med Coll Fac Hlth Sci Dept Med Biol Ul Kopernika 7 PL-31034 Krakow Poland;

Jagiellonian Univ Med Coll Fac Hlth Sci Dept Med Biol Ul Kopernika 7 PL-31034 Krakow Poland;

Jagiellonian Univ Med Coll Fac Hlth Sci Dept Med Biol Ul Kopernika 7 PL-31034 Krakow Poland;

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原文格式 PDF
正文语种 eng
中图分类药理学;
关键词
Enrofloxacin; Antibiotic; Dysbiosis; Immune environment; Tolerogenic dendritic cells;

机译：苯甲酸;抗生素;消化不良;免疫环境;耐受性树突细胞;

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1. Oral treatment with enrofloxacin creates anti-inflammatory environment that supports induction of tolerogenic dendritic cells [J] . Anna Strz?pa, Katarzyna Marcińska, Monika Majewska-Szczepanik, International immunopharmacology . 2019,第期

机译：用瑞氧氟沙星的口服处理产生抗炎环境，支持诱导耐受性树突细胞的诱导
2. Oral treatment with enrofloxacin creates anti-inflammatory environment that supports induction of tolerogenic dendritic cells [J] . Strzepa Anna, Marcinska Katarzyna, Majewska-Szczepanik Monika, International immunopharmacology . 2019,第期

机译：用瑞氧氟沙星的口服处理产生抗炎环境，支持诱导耐受性树突细胞的诱导
3. A distinct tolerogenic subset of splenic IDO +CD11b + dendritic cells from orally tolerized mice is responsible for induction of systemic immune tolerance and suppression of collagen-induced arthritis [J] . ParkM.-J., ParkK.-S., ParkH.-S., Cellular immunology . 2012,第1a2期

机译：来自口服耐受小鼠的脾脏IDO + CD11b +树突状细胞的一个独特的耐受性亚组负责诱导全身性免疫耐受和抑制胶原诱导的关节炎
4. Temporal Immunomodulator Controlled Release from Composite Scaffold for the Induction of Tolerogenic Dendritic Cells [C] . Sangeetha Srinivasan, Julia E Babensee World biomaterials congress . 2016

机译：临时免疫调节剂从复合支架中释放以诱导致耐受性树突状细胞。
5. Induction of Peripheral Regulatory T Cells and Prevention of Autoimmunity by Tolerogenic Dendritic Cells [D] . Jones, Andrew J. 2017

机译：耐受性调节性T细胞的诱导和致耐受性树突状细胞的自身免疫性预防
6. Induction of Tolerogenic Dendritic Cells by a PEGylated TLR7 Ligand for Treatment of Type 1 Diabetes [O] . Tomoko Hayashi, Shiyin Yao, Brian Crain, -1

机译：PEG化TLR7配体诱导耐受性树突状细胞治疗1型糖尿病
7. Induction of Tolerogenic Dendritic Cells by a PEGylated TLR7 Ligand for Treatment of Type 1 Diabetes. [O] . Tomoko Hayashi, Shiyin Yao, Brian Crain, 2015

机译：聚乙二醇化TLR7配体诱导致耐受树突状细胞治疗1型糖尿病。

Oral treatment with enrofloxacin creates anti-inflammatory environment that supports induction of tolerogenic dendritic cells

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