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首页> 外文期刊>International Journal of Control >Boolean network representation of a continuous-time system and finite-horizon optimal control: application to the single-gene regulatory system for the lac operon
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Boolean network representation of a continuous-time system and finite-horizon optimal control: application to the single-gene regulatory system for the lac operon

机译:布尔网络表示连续时间系统和有限地平线最佳控制:应用于LAC操纵子的单基因监管系统

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摘要

In this paper, the single-gene regulatory system for the lac operon is considered and a method to build a Boolean network able to represent its dynamics is given. A procedure, based on techniques borrowed from algebraic geometry, to compute an optimal control policy minimising a cost function is given for such a Boolean network. A tool to apply such an optimal control policy to the continuous time system is reported. The proposed control method is tested in two simulative examples.
机译:在本文中,考虑了Lac操纵子的单基因调节系统,并给出了能够构建能够代表其动态的布尔网络的方法。 基于从代数几何借用的技术的过程来计算最小化成本函数的最佳控制策略,以获得这种布尔网络。 报告了将这种最佳控制策略应用于连续时间系统的工具。 在两个模拟实施例中测试了所提出的控制方法。

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