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首页> 外文期刊>International journal of oral and maxillofacial surgery >Does platelet-rich fibrin have a role in osseointegration of immediate implants? A randomized, single-blind, controlled clinical trial
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Does platelet-rich fibrin have a role in osseointegration of immediate implants? A randomized, single-blind, controlled clinical trial

机译:富含血小板的纤维蛋白是否具有在骨整合的立即植入物的作用? 随机,单盲,受控临床试验

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摘要

Immediate implants are a valuable treatment option to replace natural teeth in the aesthetic region. The hypothesis of this randomized controlled clinical trial was that immediate implants grafted with autologous platelet-rich fibrin (PRF) have better clinical and radiographic outcomes than non-grafted controls. Forty-one implants were placed in 31 subjects with one or more non-restorable single-rooted teeth. Autologous PRF was placed in the peri-implant region of the study group (n=21) and no augmentation was done in the control group (n=20). A staged protocol was followed for implant restoration. The patients received a definitive restoration after 3 months and were followed up for a period of 1year. The statistical analysis included 39 implants sites in 29 subjects. A significant increase in implant stability was noted in both groups over the 3-month period (implant stability quotient: study group 56.58±18.81 to 71.32±7.82; control group 60.61±11.49 to 70.06±8.96;P=0.01). No significant difference was observed between the groups in terms of implant stability. The hypothesis was thus rejected, as there was no significant effect of PRF on immediate implants with adequate primary stability.
机译:即时植入物是替代审美区域中的天然牙齿的有价值的治疗选择。该随机对照临床试验的假设是接枝以自体血小板的纤维蛋白(PRF)接枝的立即植入物具有比非接枝对照的更好的临床和放射线检查。将四十一植入物置于31项受试者中,具有一种或多种不可恢复的单生牙齿。将自体PRF置于研究组(n = 21)的PERI-植入区域中,并在对照组中没有进行增强(n = 20)。术语术后术后术治疗。患者在3个月后接受过明确的恢复,并随访1年的时间。统计分析包括29个受试者中的39个植入部位。在3个月期间(植入稳定性商:研究组56.58±18.81至71.32±7.82至71.32±11.49至70.06±8.96; P = 0.01),在两组中,在两组中注意到植入稳定性的显着增加; 71.32±11.49; p = 0.01)。在植入物稳定性方面,组之间没有观察到显着差异。因此,假设被拒绝,因为PRF对具有足够初级稳定性的直接植入物没有显着影响。

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