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首页> 外文期刊>International journal of rheumatic diseases >Validation and reliability of the Timed Up and Go test for measuring objective functional impairment in patients with long‐standing rheumatoid arthritis: a cross‐sectional study
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Validation and reliability of the Timed Up and Go test for measuring objective functional impairment in patients with long‐standing rheumatoid arthritis: a cross‐sectional study

机译：长期类风湿性关节炎患者测量客观函数损伤定时和可靠性的验证及可靠性：横截面研究

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Abstract Aim This study aimed to validate the Timed Up and Go test ( TUG ) for measuring objective functional impairment in patients with established rheumatoid arthritis ( RA ) based on a prospective observational cohort of RA patients undergoing joint surgery. Methods We collected data on demographics, Health Assessment Questionnaire Disability Index ( HAQ ‐ DI ), and associations between TUG and HAQ ‐ DI and other patient‐reported outcomes, including European Quality of life scale ( EQ ‐5D) were determined. Cut‐off values of TUG for HAQ remission ( HAQ ‐ DI ≤0.5), normal HAQ ( HAQ ‐ DI ≤0.25), and the absence of disability in each HAQ ‐ DI category were also determined by age. Results A total of 435 patients were enrolled and analyzed. Mean age was 64.2 years, mean disease duration was 17.1 years, mean HAQ ‐ DI was 1.14, and mean TUG was 11.1 sec. TUG was significantly correlated with aging, EQ ‐5D, and HAQ ‐ DI categories related to lower limb function (arising, walking, reach and activity). After adjusting for age and sex, mean TUG values were 9.0 sec (95% CI , 7.7–10.3) in patients with HAQ remission and 8.7 sec (7.4–10.4) in those with normal HAQ . By age, mean TUG values for HAQ remission were 7.2 sec (5.9–8.5) in young patients (≤61 years), 9.1 sec (7.6–10.5) in middle‐aged patients (62–70 years) and 10.0 sec (5.7–14.2) in old patients (≥71 years). Conclusion TUG was significantly associated with functional impairment and aging in patients with long‐standing RA . Thus, TUG could be useful in setting treatment goals for joint surgery and rehabilitation in established RA patients.
机译：摘要目的本研究旨在验证基于接受关节手术的预期观察队患者的预期观察队列患者测量患者客观函数损伤的定时和去试验（拖船）。方法采集人口统计数据，健康评估问卷残疾指数（HAQ-DI）以及拖船和哈卡 - DI和其他患者报告的结果的关联，包括欧洲寿命尺度（EQ -5D）的协会。 HAQ缓解率的截止值（HAQ - DI≤0.5），正常HAQ（HAQ-DI≤0.25），并且每个HAQ-DI类别的缺失也是根据年龄确定的。结果共有435名患者注册和分析。平均年龄为64.2岁，平均疾病持续时间为17.1岁，意味着HAQ-DI为1.14，而平均拖拽是11.1秒。与较低肢体功能（出现，行走，达到和活动有关的老化，EQ -5D和HAQ-DI类别，Tug显着相关。调整年龄和性别后，平均拖轮值为9.0秒（95％CI，7.7-10.3），患者在HAQ缓解患者中，8.7秒（7.4-10.4），其中HAQ正常。按年龄划算，HAQ缓解的平均值为7.2秒（5.9-8.5），患者（≤61岁），9.1秒（7.6-10.5）中年患者（62-70岁）和10.0秒（5.7- 14.2）旧患者（≥71岁）。结论Tug与长期RA患者功能损伤和老化显着相关。因此，拖船可用于在已建立的RA患者中设定用于联合手术和康复的治疗目标。

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