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Comparison of Differences in Brain Structure Between Teenagers and Twenties Brain Using 3 T Magnetic Resonance Imaging

机译:3 T磁共振成像的青少年和二十脑脑结构差异的比较

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Total cerebral volume increases very rapidly in childhood, peaking in early teenage years then declining in adolescence. However, most studies quantified only one or few structures and the relative development pattern of subcortical structures is still unclear. For our study, we aim to examine the cortical, subcortical and structural changes associated with age by comparing the cortical and subcortical volumes between 52 healthy teens and 40 healthy twenties using 3 T magnetic resonance imaging (MRI). In late adolescence, volumes of gray matter (GM) decreased and white matter (WM) increased, and asymmetry between the left and right hemispheres of the brains was found to be similar between teenagers and twenties. Only occipital GM, nucleus accumbens and thalamus showed difference in asymmetry. Various previous studies have shown that studying morphological changes of developing brains can be useful in identifying certain structural abnormalities associated with psychiatric and neurological diseases modifications in the brain. Therefore, we believe our analysis of volumetric differences in cortical and subcortical structures could be helpful for identifying neurophysiological changes that occur in transition from adolescence to adulthood.
机译:儿童时期总脑体积迅速增加,早期少年达到峰值,然后在青春期下降。然而,大多数研究量化了一个或多个结构,并且皮下结构的相对发育模式仍然不明确。对于我们的研究,我们的目标是通过使用3 T磁共振成像(MRI)比较52个健康青少年和40个健康二十的皮质和皮质体积来检查与年龄相关的皮质,皮质和结构变化。在青春期晚期,灰质(GM)的体积减少,白质(WM)增加,脑子左右半球之间的不对称性在青少年和二十几岁之间存在相似。只有枕脑病,核,核心腺和丘脑在不对称性差异。各种先前的研究表明,研究发育大脑的形态变化可用于鉴定与精神病和脑中的精神病和神经疾病修饰相关的某些结构异常。因此,我们认为我们对皮质和皮质标结构的体积差异分析可能有助于鉴定从青春期到成年期发生的过渡时发生的神经生理变化。

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