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首页> 外文期刊>Acute pain: international journal of acute pain management >Addition of fentanyl to mepivacaine does not affect the duration of brachial plexus block
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Addition of fentanyl to mepivacaine does not affect the duration of brachial plexus block

机译：在甲哌卡因中加入芬太尼不会影响臂丛神经阻滞的持续时间

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摘要

Numerous studies dealing with the effects of the addition of opioids to a local anesthetic (LA) in peripheral nerve block have been published, but results are conflicting. The present study was aimed at studying the question of whether fentanyl addition to mepivacaine could improve intra- and postoperative conditions of an axillary plexus block. Methods: After institutional approval and informed consent, 51 patients (ASA I and II) undergoing plexus anesthesia for forearm and hand surgery were included into the study. Patients were randomly assigned to one of three groups: group A (50 ml mepivacaine, 15 mg ml~(-1), with 4 ml saline for nerve block and 4 ml normal saline (NS) subcutaneously), group B (50 ml mepivacaine, 15 mg ml~(-1), with 100mug fentanyl in 4ml NS for nerve block, and 4ml NS subcutaneously), or group C (50ml mepivacaine, 15mgml~(-1), with 4ml NS for nerve block and 100 mug fentanyl in 4ml saline subcutaneously). Visual analogue score (VAS), sensory block, motor block and hemodynamics were recorded prior to and 5, 10, 30 and 60 min and 2, 3,4,12 and 24 h after induction of the block. Results: There were no differences in VAS scores, time to administration of the first postoperative dose of an analgesic, or the total dose of analgesic given postop. No differences with respect to the intensity of sensory block and motor block or time to onset of block were observed. Conclusions: Addition of 100 mug fentanyl to mepivacaine, 15mgml~(-1), does not affect the quality of anesthesia of brachial plexus block.
机译：已经发表了许多关于在外周神经阻滞中向局部麻醉药（LA）添加阿片类药物的影响的研究，但结果相矛盾。本研究旨在研究芬太尼在甲哌卡因中是否可以改善腋窝神经丛阻滞的术中和术后状况。方法：经机构批准和知情同意后，将51例接受神经丛麻醉的前臂和手部手术患者（ASA I和II）纳入研究。患者被随机分为三组之一：A组（50 ml甲哌卡因，15 mg ml〜（-1），4 ml生理盐水用于皮下注射和4 ml生理盐水（皮下注射）），B组（50 ml mepivacaine） ，15 mg ml〜（-1），100 ml芬太尼，4 ml NS用于神经阻滞和4ml NS皮下注射）或C组（50ml mepivacaine，15mgml〜（-1），4ml NS用于神经阻滞和100杯芬太尼在4ml盐水中皮下注射）。视觉模拟评分（VAS），感觉阻滞，运动阻滞和血流动力学在阻滞诱发之前，5、10、30和60分钟以及2、3、4、12和24小时之前记录。结果：VAS评分，术后第一次使用镇痛药的时间或术后给予镇痛药的总剂量没有差异。在感觉障碍和运动障碍的强度或障碍发作的时间方面未观察到差异。结论：在甲哌卡因中加入100杯芬太尼15mgml〜（-1）不会影响臂丛神经阻滞的麻醉质量。

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