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首页> 外文期刊>International journal of psychiatry in clinical practice >Unconjugated bilirubin and acute psychosis: a five years retrospective observational and controlled study in patients with schizophrenia, schizoaffective and bipolar disorders
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Unconjugated bilirubin and acute psychosis: a five years retrospective observational and controlled study in patients with schizophrenia, schizoaffective and bipolar disorders

机译：未经舒适的胆红素和急性精神病：精神分裂症患者的五年来看，对照研究，SchizoAfecceive和双相障碍

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Introduction: Unconjugated bilirubin (UCB) high levels have been correlated with schizophrenia spectrum disorders. Methods: We searched for correlation between UCB mean levels, duration of psychiatric admission, and diagnosis in 255 individuals, including 56 healthy controls and 199 acute patients (namely 44 with schizophrenia, 99 with schizoaffective disorder and 56 with bipolar disorder). Results: We found a statistically significant difference between UCB mean levels of patients with schizophrenia versus patients with schizoaffective (0.41 mg/dL vs. 0.34 mg/dL; p < .03) and bipolar disorders (0,41 mg/dL vs. 0.29mg/dL; p < .0001). We also found a statistically significant difference between UCB mean levels of patients with schizoaffective disorder and bipolar disorder (0.34 mg/dL vs. 0.28; p < .04). We also found a significant difference (p < .001) between mean admission duration of schizophrenia (29 days) versus bipolar patients (16 days). Although in a non-significant manner, the schizoaffective group got a mean admission duration value (22 days) right in between the schizophrenia and the bipolar patients. Conclusions: Our results deserve further research to access the role UCB may have in the physiopathology of acute patients with schizophrenia/schizoaffective/bipolar spectrum disorders.Keypoints Unconjugated Bilirubin (UCB) high levels are correlated with acute psychosis. UCB high levels are correlated with duration of psychiatric admission. UCB mean levels of schizophrenic patients are higher than schizoaffective patients. UCB mean levels of schizoaffective patients are higher than bipolar patients.
机译：简介：未经舒适的胆红素（UCB）高水平与精神分裂症谱系统障碍相关。方法：我们搜索了UCB平均水平，精神疾病持续时间和255人的诊断的相关性，包括56名健康对照和199例急性患者（即44例具有精神分裂症，99例，带有双相情感障碍和56例。结果：我们发现了精神分裂症患者的UCB平均水平之间的统计学差异（0.41mg / d1.0.34mg / dl; p <.03）和双极性疾病（0,41mg / dl与0.29 mg / dl; p <.0001）。我们还发现UCB平均患者患者的患者的统计学上有显着差异（0.34mg / dl vs.0.28; p <.04）。我们还发现了精神分裂症（29天）与双极患者（16天）之间的平均入院持续时间之间的显着差异（P <.001）。虽然以非显着的方式，SchizoAffective组在精神分裂症和双相患者之间进行了平均入院持续时间值（22天）。结论：我们的结果应试得进一步研究访问中，UCB在急性精神分裂症/脑谱患者的急性患者患者身体病理学中的作用。令人遗症的胆红素（UCB）高水平与急性精神病症相关。 UCB高水平与精神科入院的持续时间相关。 UCB平均精神分裂症患者的平均水平高于SchizoAfferive患者。 UCB平均脑蛋糕患者的平均水平高于双极患者。

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