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首页> 外文期刊>Eating and weight disorders: EWD >Psychopathology in underweight and weight-recovered females with anorexia nervosa
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Psychopathology in underweight and weight-recovered females with anorexia nervosa

机译：厌食症神经系统体重和重量恢复女性的精神病理学

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摘要

OBJECTIVE: To compare general and eating disorder-specific psychopathology in patients with acute anorexia nervosa (acAN), weight-recovered patients (recAN) and healthy control women (HCW). METHODS: One hundred anorexia nervosa patients (66 acAN and 34 recAN) and 88 HCW were included in our study. Psychopathology was assessed by self-report questionnaires [Symptom Check List 90 Revised (SCL-90-R), Eating Disorder Inventory-2 (EDI-2)] as well as by interview [Structured Interview of Anorexia Nervosa and Bulimic Syndromes (SIAB-EX)] and compared using multivariate analysis of variance. Plasma leptin levels were determined using enzyme linked immunosorbent assay. RESULTS: Mean comparisons indicated highly significant differences between acAN and recAN subjects on all psychopatholgy variables, except for perfectionism. RecAN subjects did not differ from HCW. Partial weight recovery was associated with decreasing levels of psychopathology. Correlational analyses suggested strong negative associations between leptin levels and psychopathology. CONCLUSION: Prolonged malnutrition, as indicated by suppressed plasma leptin levels, is strongly related to eating disorder-specific as well as general psychopathological symptoms. Weight recovery is associated with the absence of psychopathology. These data emphasize the interaction between somatic and psychological variables.
机译：目的：比较急性厌食症（Acan），体重恢复患者（核心）和健康对照女性（HCW）患者患者的综合和吃障碍特异性精神病理学。方法：在我们的研究中纳入一百个厌食症患者（66 Acan和34次常规）和88个HCW。通过自我报告调查问卷评估精神病理学[症状检查清单90修订（SCL-90-R），饮食障碍库存-2（EDI-2）以及访谈[结构化访谈厌食症和肥胖综合征（SIAB- EX）]并使用多元差异分析比较。使用酶联免疫吸附测定测定血浆瘦素水平。结果：平均比较表明，除了完美主义外，Acan与recan受试者之间的高度显着差异，除了完美主义。重新审核受试者与HCW没有不同。部分重量恢复与降低的精神病理学水平有关。相关分析表明瘦素水平与精神病理学之间的强负关联。结论：抑制血浆瘦素水平的表明，延长营养不良与吃障碍特异性以及一般的精神病理学症状有关。重量恢复与心理病理学的缺失有关。这些数据强调了体细胞和心理变量之间的相互作用。

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  • 来源
    《Eating and weight disorders: EWD》 |2009年第4期|共7页
  • 作者

    SchneiderN.; Salbach-AndraeH.; MerleJ.V.; HeinJ.; PfeifferE.; LehmkuhlU.; EhrlichS.;

  • 作者单位

    Department of Child and Adolescent Psychiatry Psychosomatics and Psychotherapy CVK Berlin;

    Department of Child and Adolescent Psychiatry Psychosomatics and Psychotherapy CVK Berlin;

    Department of Child and Adolescent Psychiatry Psychosomatics and Psychotherapy CVK Berlin;

    Department for Psychiatry CCM Charité - Universit?tsmedizin Berlin Germany;

    Department of Child and Adolescent Psychiatry Psychosomatics and Psychotherapy CVK Berlin;

    Department of Child and Adolescent Psychiatry Psychosomatics and Psychotherapy CVK Berlin;

    Department of Child and Adolescent Psychiatry Psychosomatics and Psychotherapy CVK Berlin;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 内分泌腺疾病及代谢病;
  • 关键词

    Anorexia nervosa; Leptin; Psychopathology; Weight recovery;

    机译：厌食症;瘦素;精神病理学;体重恢复;

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