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首页> 外文期刊>Acute pain: international journal of acute pain management >Efficacy of a homeopathic preparation in control of post-operative pain-A pilot clinical trial
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Efficacy of a homeopathic preparation in control of post-operative pain-A pilot clinical trial

机译:顺势疗法制剂在控制术后疼痛中的功效-一项初步临床试验

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Background: Despite modern surgical technique and anaesthesia, post-operative pain following ambulatory surgery remains an important cause of delayed hospital discharge, readmission, and post-operative visits to primary care physician. Traumeel S~R is a homeopathic complex preparation widely used in German speaking Europe for trauma and orthopaedic pain. Methods: We performed an open, quasi-randomized triple-arm clinical trial to evaluate the efficacy of two regimens of Traumeel S~R in minimizing post-operative pain and analgesic consumption following elective Hallux valsus surgery. A total of 30 patients were assigned to the single injection, the injection + oral intake (PO) or the control group. Repeated measures of maximal pain at rest during 13 days postoperative were evaluated using a linear mixed effects model. The total consumption of analgesics was also compared between the three groups. Results: The single injection and injection + PO groups experienced lower pain scores as compared to the control group (p = 0.02 and 0.05, respectively). There was no significant difference between the single injection group and the injection + PO groups. Similarly, the mean total consumption of analgesics was lower in the single injection and the injection + PO groups than in the control group but the difference was not statistically significant. Conclusion: In this pilot study, Traumeel S~r demonstrated efficacy in minimizing post-operative pain following repair of H. valgus. These promising results should be validated in a randomized, double-blinded, placebo controlled trial.
机译:背景:尽管采用了现代手术技术和麻醉方法,但非卧床手术后的术后疼痛仍然是延迟出院,再次入院以及术后就诊至基层医疗医生的重要原因。 Traumeel S〜R是一种顺势疗法复合制剂,在欧洲德语区广泛用于治疗创伤和骨科疼痛。方法:我们进行了一项开放,准随机的三臂临床试验,以评估Traumeel S〜R两种方案在选择性Hallux valsus手术后最大程度地减少术后疼痛和止痛药的疗效。共有30名患者被分配为单次注射,注射+口服摄入量(PO)或对照组。使用线性混合效应模型评估术后13天休息时最大疼痛的重复测量。还比较了三组之间镇痛药的总消耗量。结果:与对照组相比,单次注射组和注射+ PO组的疼痛评分更低(分别为p = 0.02和0.05)。单次注射组和注射+ PO组之间无显着差异。同样,单次注射和注射+ PO组的平均镇痛剂总消耗量低于对照组,但差异无统计学意义。结论:在这项初步研究中,Traumeel S〜r证明可最大程度地减少外翻H.修复后的术后疼痛。这些有希望的结果应在随机,双盲,安慰剂对照试验中进行验证。

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