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首页> 外文期刊>BJU international >The risk of prostate cancer amongst South Asian men in southern England: the PROCESS cohort study.
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The risk of prostate cancer amongst South Asian men in southern England: the PROCESS cohort study.

机译：英格兰南部的南亚男性患前列腺癌的风险：PROCESS队列研究。

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OBJECTIVE: To reinvestigate whether South Asian men in the UK are at lower risk of being diagnosed with prostate cancer in a UK-based retrospective cohort study and to examine possible reasons that may explain this. PATIENTS AND METHODS: The catchment areas were predefined in four areas of southern England, and age- and race-specific populations for those areas taken from census data. Cases were ascertained through review of multiple hospital sources, while race, other demographic factors, and medical history were determined using questionnaires sent to the men, hospital records review and death certificates. The South Asian group included men of Indian, Bangladeshi and Pakistani origin. RESULTS: There was modest evidence of lower prostate cancer rates in South Asian men compared with their White neighbours (age-adjusted rate ratio 0.81; 95% confidence interval 0.65-1.00). This difference did not reflect less use of prostate-specific antigen (PSA) testing or differences in clinical features at presentation. CONCLUSION: This study provides evidence of a lower incidence of prostate cancer amongst South Asian men living in England, in comparison with their White counterparts. If anything, South Asian men presented with clinical features of earlier disease suggesting that the reduced risk is unlikely to be an artefact of poorer access to health care.
机译：目的：在一项基于英国的回顾性队列研究中，重新调查英国的南亚男性是否被诊断出患有前列腺癌的风险较低，并研究可能的原因。患者和方法：在英格兰南部的四个地区预先定义了集水区，并根据普查数据对这些地区的年龄和种族进行了分类。通过复查多个医院来确定病例，同时使用发给男性的问卷，住院记录复查和死亡证明确定种族，其他人口统计学因素和病史。南亚人群包括印度，孟加拉和巴基斯坦血统的人。结果：有适度的证据表明，与白人邻居相比，南亚男性的前列腺癌发病率更低（年龄调整率比率0.81; 95％置信区间0.65-1.00）。这种差异并未反映出较少使用前列腺特异性抗原（PSA）测试，也没有反映临床表现的差异。结论：这项研究提供了证据，与白人相比，居住在英格兰的南亚男性的前列腺癌发病率更低。如果有的话，南亚男性表现出较早疾病的临床特征，这表明降低风险的可能性不大可能是获得较差医疗服务的假象。

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