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Electrochemical Detection of Zika Virus in Biological Samples: A Step for Diagnosis Point-of-care

机译:生物样品中Zika病毒的电化学检测:诊断诊断点的步骤

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摘要

This work describes an electrochemical genosensor for detection of genomic RNA of Zika virus in real samples of infected patients, using a new platform based on graphite electrodes modified with electrochemically reduced graphene oxide and polytyramine-conducting polymer. The developed genosensor was suitable for differentiation between samples of healthy and infected patients with Zika virus by differential pulse voltammetry, detecting up to 0.1 fg/mL (1.72 copies/mL), showing good stability (about 60 days), rapid analysis (about 20 min) and potential for filling the lack of practical diagnostic methods for Zika virus.
机译:这项工作描述了一种用于检测受感染患者的真实样本的Zika病毒基因组RNA的电化学遗传传感器,使用基于电化学还原的石墨烯氧化物和聚盐传导聚合物改性的石墨电极。 开发的毒素传感器适用于通过差分脉冲伏安法测定Zika病毒的健康和感染患者样品之间的分化,检测到0.1fg / ml(1.72拷贝/ ml),显示出良好的稳定性(约60天),快速分析(约20 分钟)和填补Zika病毒缺乏实用诊断方法的可能性。

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