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首页> 外文期刊>Electroanalysis >Disposable Biosensor Based on Amidase/CeO2/GNR Modified Inkjet-printed CNT Electrodes-droplet Based Paracetamol Detection in Biological Fluids for 'Point-of-care' Applications
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Disposable Biosensor Based on Amidase/CeO2/GNR Modified Inkjet-printed CNT Electrodes-droplet Based Paracetamol Detection in Biological Fluids for 'Point-of-care' Applications

机译:基于酰胺酶/ CEO2 / GNR的一次性生物传感器改性喷墨印刷的CNT电极 - 液滴在生物流体中的扑热胺检测,用于“护理点”应用

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摘要

A disposable acetaminophen biosensor based on inkjet-printed CNT electrodes (IJPCNT) modified with amidase/cerium dioxide@graphene nanoribbons composite was developed (ACeO2@GNR/IJPCNT). The enzyme amidase A was used for the first time as a recognition element. Inkjet-printed CNT electrodes served as a basis for the construction of a biosensor that enables droplet detection using 5 mu L sample volume. The biosensor showed high selectivity, sensitivity, a low detection limit of 0.18 mu M and a wide working linear range from 1 to 100 mu M. The proposed approach allows fast and reliable detection of acetaminophen in biological fluids with negligible matrix effect and remarkable reproducibility.
机译:开发了一种基于喷墨印刷的CNT电极(IJPCNT)的一次性乙酰氨基酚生物传感器(IJPCNT),进行了用酰胺酶/二氧化铈@ Graphene NanoRibbons复合材料(Aceo2 @ GNR / IJPCNT)。 作为识别元件首次使用酶酰胺酶A. 喷墨印刷的CNT电极作为构建生物传感器的基础,其能够使用5μL样品体积来实现液滴检测。 生物传感器显示出高选择性,灵敏度,低检测限为0.18μm,宽工作线性范围为1至100μm。该方法允许在生物流体中快速可靠地检测生物流体中的乙酰氨基酚,其基质效应和显着的再现性。

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