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首页> 外文期刊>BJU international >Semen cryopreservation after orchidectomy in men with testicular cancer.
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Semen cryopreservation after orchidectomy in men with testicular cancer.

机译:睾丸癌男性兰花切除术后精液冷冻保存。

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摘要

OBJECTIVE: To assess the feasibility of semen cryopreservation after orchidectomy in patients with testicular tumour. PATIENTS AND METHODS: The quality of semen samples was investigated in 36 men with testicular tumour (mean age 31.7 years, range 20-49) who were referred to our infertility centre for semen cryopreservation. For each patient, the number of straws, semen volume, number of spermatozoa, and sperm motility before and after freezing were evaluated. RESULTS: Fifteen patients (42%) banked sperm before and 21 (58%) after orchidectomy; the delay was >7 days in 19 patients (53%). The mean age, histological diagnosis and tumour stage did not differ significantly whatever the time of cryopreservation. Semen quality did not differ significantly in patients who cryopreserved sperm before or after orchidectomy and there were no significant differences in sperm values whatever the delay before preservation. Semen quality was the same in patients with seminoma or nonseminoma tumour. CONCLUSION: These findings indicate that spermatogenesis of the contralateral testis is sufficient for successful semen cryopreservation after orchidectomy. Urologists should be encouraged to increase the awareness among oncology teams and patients about the new developments in preserving fertility for patients with cancer.
机译:目的:评估睾丸肿瘤患者兰花切除术后精液冷冻保存的可行性。患者与方法:对36名睾丸肿瘤男性患者(平均年龄31.7岁,范围20-49)进行了精液质量检查,这些患者被送至我们的不育不育中心进行冷冻保存。对于每个患者,评估冷冻前后的吸管数量,精液量,精子数量和精子活力。结果:兰花切除前有15例患者(42%)有精子存留,兰花切除后有21例(58%)有精子存留。 19名患者(53%)的延迟时间超过7天。无论冷冻保存时间如何,平均年龄,组织学诊断和肿瘤分期均无显着差异。在兰花切除术之前或之后冷冻保存精子的患者精液质量没有显着差异,并且无论保存前的延迟如何,精子值均无显着差异。精原细胞瘤或非精原细胞瘤患者的精液质量相同。结论:这些发现表明对侧睾丸的精子发生足以成功完成兰花切除术后精液冷冻保存。应当鼓励泌尿科医师提高肿瘤学团队和患者对保留癌症患者生育能力的新进展的认识。

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