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首页> 外文期刊>European journal of neurology: the official journal of the European Federation of Neurological Societies >The idiopathic normal‐pressure hydrocephalus Radscale: a radiological scale for structured evaluation
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The idiopathic normal‐pressure hydrocephalus Radscale: a radiological scale for structured evaluation

机译：特发性正常压力脑辐射辐射：结构化评价的放射尺度

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Background and purpose Despite the important role of imaging in diagnosing idiopathic normal‐pressure hydrocephalus (iNPH), a structured overall assessment of radiological signs is still lacking. The purpose of this study was to construct a radiological scale, composed of morphological signs of iNPH, and compare it with clinical symptoms. Methods In this prospective, population‐based study of iNPH, 168 individuals (93 females) [mean age 75 (range 66–92)?years] underwent computed tomography of the brain and a neurological examination with assessment of clinical symptoms according to Hellstr?m's iNPH scale. Two radiologists, blinded to clinical data, independently evaluated and measured eight radiological parameters, i.e. Evans’ index, callosal angle, size of temporal horns, narrow high‐convexity sulci, dilated Sylvian fissures, focally dilated sulci, peri‐ventricular hypodensities and bulging of the lateral ventricular roof. Results In a linear regression model, all parameters except ventricular roof bulging were significantly associated with clinical iNPH symptoms. The seven remaining parameters were summarized into a total iNPH Radscale score ranging from 0 to 12. There was a significant correlation ( r ?=?0.55, P? ? 0.001) between the total iNPH Radscale score and clinical symptoms. The inter‐rater agreement for the included radiological parameters was high (intraclass correlation, 0.74–0.97). Conclusion The iNPH Radscale may become a valuable diagnostic screening tool, allowing a structured radiological assessment. A high iNPH Radscale score together with clinical symptoms should raise suspicion of iNPH, motivating further evaluation for shunt surgery.
机译：背景以来，尽管成像在诊断特发性正常压力脑积水（INPH）中的重要作用，但仍然缺乏缺乏放射性迹象的结构化整体评估。本研究的目的是构建一种放射线测量，由inph的形态学迹象组成，并将其与临床症状进行比较。在这一前瞻性的方法中，基于人口的INPH，168个人（93名女性）[平均年龄75（范围66-92）吗？岁月的计算断层扫描和神经学检查，评估临床症状的评估根据地狱般的临床症状吗？米的别号规模。两个放射科医生，盲目的临床数据，独立评估和测量八个放射性参数，即埃文斯的指数，调用角度，颞喇叭的大小，狭窄的高凸硫菌，扩张Sylvian裂缝，局部扩张舒尔，静脉沉积和凸起。侧卧性屋顶。结果在线性回归模型，与临床视网膜症状外，患心室屋顶凸出的所有参数。七个剩余参数总结为从0到12的总inph Radscale分数。在总视灰质辐射分数和临床症状之间存在显着的相关性（R？= 0.55，p≤0.55，p≤0..001）。纳入放射性参数的评估间协议很高（颅内相关，0.74-0.97）。结论inph Radscale可能成为有价值的诊断筛查工具，允许结构化放射性评估。高inph Radscale得分与临床症状应举起嫌疑，激发进一步评估分流手术。

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