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首页> 外文期刊>European journal of cancer care >Heads Up: a pilot trial of a psychological intervention to improve nutrition in head and neck cancer patients undergoing radiotherapy
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Heads Up: a pilot trial of a psychological intervention to improve nutrition in head and neck cancer patients undergoing radiotherapy

机译：抬头：对心理干预的试验试验，以改善放射治疗的头部和颈部癌症患者的营养

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Malnutrition in head and neck cancer (HNC) patients is common and associated with poorer radiotherapy outcomes including increased mortality. This pilot trial investigates the feasibility and effectiveness of a psychological intervention to improve nutritional status, depression and mortality in HNC patients undergoing radiotherapy. Fifty-nine intervention patients received motivational interviewing and cognitive behavioural therapy compared to 70 historical controls who received treatment as usual. Participants were assessed for nutrition, depression and mortality. There were no significant differences between groups in nutritional status, depression or mortality. Subgroup analyses among patients at greater nutritional risk (cancers of the oral cavity, pharynx, larynx) revealed a potentially clinically important reduction on the PG-SGA and lower mortality (31% of controls vs. 16% intervention; P=0.03) in favour of the intervention condition. Potential benefits in nutritional status and in mortality in this pilot trial of a psychological intervention among HNC patients at high nutritional risk suggest that a larger randomised controlled trial is warranted.
机译：头部和颈部癌症（HNC）患者的营养不良是常见的，与较差的放疗结果相关，包括增加死亡率。该试点试验调查了心理干预的可行性和有效性，以改善接受放射治疗的HNC患者的营养状况，抑郁和死亡率。 59例干预患者接受了诱导的面试和认知行为治疗，而70历史控制相比通常接受常规治疗。参与者被评估为营养，抑郁和死亡率。营养状况，抑郁或死亡率之间的群体之间没有显着差异。亚群分析更大的营养风险（口腔腔内，咽部，喉部）的患者揭示了PG-SGA和降低死亡率的可能性临床上重要的降低（31％的对照与16％的干预; P = 0.03），有利于干预条件。在高营养风险下，本试验试验中营养状况和死亡率的潜在益处和死亡率在高营养风险下的患者心理干预表明，有必要进行更大的随机对照试验。

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