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首页> 外文期刊>European journal of cancer prevention: The official journal of the European Cancer Prevention Organisation (ECP) >Cervical cancer screening and subsequent procedures in women under the age of 25 years between 2007 and 2013 in France: a nationwide French healthcare database study
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Cervical cancer screening and subsequent procedures in women under the age of 25 years between 2007 and 2013 in France: a nationwide French healthcare database study

机译：2007年至2013年在法国2007年至2013年期间的宫颈癌筛查和后续程序在2007年至2013年期间：全国范围的法国医疗保健数据库研究

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Cervical cancer screening in young women may lead to the detection of lesions with a high potential for spontaneous regression and no benefit of surgery. French guidelines recommend initiating cervical cancer screening by the Pap test from the age of 25 years. To date, no French nationwide study has assessed cervical cancer screening in young women and the related subsequent work-up and surgical procedures among screen-positive women. Using data from the French national healthcare databases (around 50 million beneficiaries), annual and 3-year Pap test screening rates were calculated among women aged 15-24 years between 2007 and 2013. Cervical excisional procedures were assessed during the 15-month period following a first Pap test in women aged 20-24 years in 2007 and 2012. About 10% of the almost six million women aged 15-65 years with at least one annual Pap test were under the age of 25, mainly women aged 20-24 years, in whom the 3-year screening coverage was 35.5% in 2013. In screened women aged 20-24 years, human papillomavirus testing rates increased markedly over the study period (+105%) and surgical management became less conservative with an increased rate of both conization (+16.5%) and other excisional treatments (+74.5%). Nevertheless, because of the overall decrease in screening coverage, the absolute yearly number of women who underwent conization decreased from 1974 to 1766 between 2007 and 2012. Higher adherence to guidelines is needed to reduce the burden of surgical treatment that is potentially associated with adverse obstetric outcomes among women under the age of 25 years.
机译：颈癌癌筛查的年轻女性可能会导致检测具有高潜力的病变，以促使自发性回归，并且没有手术的好处。法语指南建议从25岁开始的PAP测试启动宫颈癌筛查。迄今为止，没有法国全国性研究评估了患有颈部癌症的宫颈癌筛查以及屏幕阳性妇女之间的相关随后的后续处理和外科手术。使用来自法国国家医疗数据库（约5000万台受益者），年度和3年的PAP测试筛查率在2007年至2013年期间的15-24岁之间计算。在15个月期间评估了宫颈切除程序2007年和2012年20-24岁女性的第一次PAP试验。占15-65岁的近六百万个患者的10％，至少有一项年度PAP检验为25岁，主要是20-24岁年份，2013年3年的筛查覆盖率为35.5％。在20-24岁的筛查妇女中，人类乳头瘤病毒检测率明显增加（+ 105％），手术管理变得较低的保守率锥化（+ 16.5％）和其他切除治疗（+ 74.5％）。然而，由于筛选覆盖范围的总体下降，接受联盟的绝对年数从1974年至1766年之间减少到2007年至2012年。需要更高遵守指导方针，以减少可能与不良产科有关的手术治疗的负担25岁以下妇女的成果。

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