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首页> 外文期刊>European journal of gynaecological oncology >Uterine endometrial stromal sarcoma revealed after treatment of uterine fibroid with ulipristal acetate: a case report
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Uterine endometrial stromal sarcoma revealed after treatment of uterine fibroid with ulipristal acetate: a case report

机译：子宫子宫内膜中间肉瘤患者尿素醋酸尿嘧啶治疗后揭示：案例报告

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Background: High-grade endometrial stromal sarcomas (ESS) are very rare uterine tumors which grow from endometrial stroma and include less than 2% of uterine malignant tumors. Preoperatively it is often difficult to diagnose these tumors due to its image of benign tumors. The authors present a first in the literature, case of a 47-year-old patient with high-grade ESS diagnosed in histopathological examination after treatment with ulipristal acetate. Case Report: Patient was operated with recognition of leiomyoma and was after three months treatment of uterine fibroid with ulipristal acetate. The histopathological examination revealed a high grade ESS and endometrium had the features of hyperplasia without atypia. One month after fast operation, patient was reoperated to expand surgery according to oncologic protocol and remove cervix, adnexa, pelvic and pars-aortic lymph nodes, and explore pelvic and abdominal cavity. All these organs were without neoplastic features. Patient was qualified to postoperative radiation and chemotherapy. Conclusions: In ESS hormone receptors are usually positive and activity of progesterone receptor modulators can influence on course of disease. This case report suggests that the patients qualification for treatment should be preceded by careful and precise clinical examination with precise ultrasound assessment of myoma, flow in uterine arteries, and pattern of flow inside fibroid tumor.
机译：背景：高档子宫内膜基质肉瘤（ESS）是非常罕见的子宫肿瘤，其从子宫内膜基质生长，包括少于2％的子宫恶性肿瘤。由于其良性肿瘤的形象，术前常难以诊断这些肿瘤。作者呈现出在文献中的第一个，案例为47岁的患者，患有尿醋酸脲治疗后被诊断为组织病理学检查的高档ESS。案例报告：患者识别平滑肌瘤，并在尿乙酸脲酸盐治疗子宫肌瘤三个月后。组织病理学检查显示出高档ESS和子宫内膜具有过增生的特征，没有Atypia。快速运行后一个月，重新进入患者以根据肿瘤方案扩大手术，并删除子宫颈，adnexa，盆腔和析波淋巴结，并探索盆腔和腹腔。所有这些器官都没有肿瘤功能。患者有资格术后辐射和化疗。结论：在ESS激素受体通常是孕激素受体调节剂的阳性和活性可以对疾病的过程影响。本案例报告表明，患者的治疗资格应在精心精确的临床检查之前，用肌瘤的精确超声评估，子宫动脉流动，以及纤维虫肿瘤的流动模式。

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