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首页> 外文期刊>European Journal of Radiology >Emphysema quantification on low-dose CT using percentage of low-attenuation volume and size distribution of low-attenuation lung regions: Effects of adaptive iterative dose reduction using 3D processing
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Emphysema quantification on low-dose CT using percentage of low-attenuation volume and size distribution of low-attenuation lung regions: Effects of adaptive iterative dose reduction using 3D processing

机译：低剂量CT的肺气肿定量使用低衰减肺区的低衰减容积和尺寸分布百分比：使用3D加工的自适应迭代剂量减少的影响

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摘要

Purpose To evaluate the effects of adaptive iterative dose reduction using 3D processing (AIDR 3D) for quantification of two measures of emphysema: percentage of low-attenuation volume (LAV%) and size distribution of low-attenuation lung regions.Method and materials: Fifty-two patients who underwent standard-dose (SDCT) and low-dose CT (LDCT) were included. SDCT without AIDR 3D, LDCT without AIDR 3D, and LDCT with AIDR 3D were used for emphysema quantification. First, LAV% was computed at 10 thresholds from -990 to -900 HU. Next, at the same thresholds, linear regression on a log-log plot was used to compute the power law exponent (D) for the cumulative frequency-size distribution of low-attenuation lung regions. Bland-Altman analysis was used to assess whether AIDR 3D improved agreement between LDCT and SDCT for emphysema quantification of LAV% and D.Results The mean relative differences in LAV% between LDCT without AIDR 3D and SDCT were 3.73%-88.18% and between LDCT with AIDR 3D and SDCT were -6.61% to 0.406%. The mean relative differences in D between LDCT without AIDR 3D and SDCT were 8.22%-19.11% and between LDCT with AIDR 3D and SDCT were 1.82%-4.79%. AIDR 3D improved agreement between LDCT and SDCT at thresholds from -930 to -990 HU for LAV% and at all thresholds for D.Conclusion AIDR 3D improved the consistency between LDCT and SDCT for emphysema quantification of LAV% and D.
机译：目的，用于评估使用3D处理（AIDR 3D）进行适应性迭代剂量减少的影响，以定量两种肺气肿措施：低衰减量（LAV％）和低衰减肺部尺寸分布的百分比。方法和材料：五十-TWO接受标准剂量（SDCT）和低剂量CT（LDCT）的患者。没有AIDR 3D的SDCT，没有AIDR 3D的LDCT和IDR 3D的LDCT用于肺气肿量化。首先，从-990到-900胡锦涛的10阈值计算Lav％。接下来，在相同的阈值处，使用对数曲线图上的线性回归来计算低衰减肺部区域的累积频率尺寸分布的电力律指数（d）。 Bland-Altman分析用于评估AIDR 3D是否改善了LDCT和SDCT之间的协议，用于LAV％和D.Result，LDCT在没有AIDR 3D和SDCT之间的LDCT之间的平均相对差异为3.73％-88.18％和LDCT之间的3.73％-88.18％使用AIDR 3D和SDCT为-6.61％至0.406％。没有AIDR 3D和SDCT之间的LDCT与SDCT之间的平均相对差异为8.22％-19.11％，并且在LDCT与AIDR 3D和SDCT之间为1.82％-4.79％。 Aidr 3D在LDCT和SDCT之间改善了-930至-990 HU的LDCT和SDCT的协议，用于LAV％，并且对于D.Conclusion AIDR 3D的所有阈值改善了LDCT和SDCT之间的一致性，用于储存液和D的肺气肿定量。

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  • 来源
    《European Journal of Radiology》 |2014年第12期|共9页
  • 作者

    NishioM.; MatsumotoS.; SekiS.; KoyamaH.; OhnoY.; FujisawaY.; SugiharaN.; YoshikawaT.; SugimuraK.;

  • 作者单位

    Advanced Biomedical Imaging Research Center Kobe University Graduate School of Medicine 7-5-2;

    Advanced Biomedical Imaging Research Center Kobe University Graduate School of Medicine 7-5-2;

    Division of Radiology Department of Radiology Kobe University Graduate School of Medicine 7-5-2;

    Division of Radiology Department of Radiology Kobe University Graduate School of Medicine 7-5-2;

    Advanced Biomedical Imaging Research Center Kobe University Graduate School of Medicine 7-5-2;

    Toshiba Medical Systems Corporation 1385 ShimoishigamiOtawara Tochigi Japan;

    Toshiba Medical Systems Corporation 1385 ShimoishigamiOtawara Tochigi Japan;

    Advanced Biomedical Imaging Research Center Kobe University Graduate School of Medicine 7-5-2;

    Division of Radiology Department of Radiology Kobe University Graduate School of Medicine 7-5-2;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 放射医学;
  • 关键词

    COPD; Iterative reconstruction; Low-dose CT; Quantitative evaluation;

    机译：COPD;迭代重建;低剂量CT;定量评估;

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