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首页> 外文期刊>European geriatric medicine. >O-44: A prospective cohort study on the effects of geriatric rehabilitation following acute exacerbations of COPD [1]
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O-44: A prospective cohort study on the effects of geriatric rehabilitation following acute exacerbations of COPD [1]

机译：O-44：一种预期队列研究COPD急性加剧后病灶康复的影响[1]

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Introduction: Older patients with COPD, hospitalized for an acute exacerbation, often do not receive recommended postacute pulmonary rehabilitation. This underuse might be related to the impaired functional status of these patients, who are more likely to present with frailty, comorbidities, and disability. Having developed and implemented a geriatric rehabilitation program for these patients (GR COPD), the primary aim of this study was to investigate the effectiveness of this program. Methods: A prospective cohort study with a three-month follow-up period. Patients were eligible when hospitalized due to an acute exacerbation of COPD and indicated for the GR_COPD program. Patients who declined the GR COPD program were considered as controls. Primary outcome was defined as change in disease-specific health status measured with the clinical COPD questionnaire (CCQ), secondary outcome as the exacerbation rate ratio during follow-up. To balance potential confounders between the intervention and control group, propensity score-based weighted linear regression analyses were performed. Results: Of the 158 included patients [78 (49.4%) male, mean age 70.8 (± 8.1) years, mean FEV1 35.5 (± 12.8) as % of predicted], 78 received the GR_COPD program. The results showed a clinically relevant treatment effect of - 0.56 points (CI - 0.89 to - 0.23; p = 0.001). Patients in the control group had 2.77 times more exacerbations compared with the intervention group [CI 2.13 to 3.58; p < 0.001]. Conclusion: This study shows a clinically relevant effect of the GR_COPD program on disease-specific health status and exacerbation rate. Implementation of the program for older patients with severe COPD hospitalized for an acute exacerbation is recommended.
机译：简介：老年COPD患者，住院治疗急性加剧，往往不会收到推荐的肺部肺康复。这种欠利用可能与这些患者的功能状况受损有关，他们更有可能呈现出脆弱，合并症和残疾。为这些患者制定并实施了一个老年人康复计划（GR COPD），本研究的主要目的是调查该计划的有效性。方法：采用三个月的随访期限进行了一个潜在的队列研究。由于COPD的急性加剧，患者有资格符合住院治疗，并为GR_COPD计划表示。拒绝GR COPD计划的患者被视为对照。主要结果被定义为临床COPD问卷（CCQ）测量的疾病特异性健康状况的变化，后续行动期间作为加剧率比的次要结果。为了平衡干预和对照组之间的潜在混淆，进行了基于倾向的基于加权线性回归分析。结果：158名包括患者[78（49.4％）男性，平均年龄为70.8（±8.1）年，平均值为预测的百分比，78个收到GR_COPD计划。结果显示临床相关的治疗效果 - 0.56点（CI - 0.89至-0.23; P = 0.001）。对照组的患者与干预组相比，加剧了2.77倍[CI 2.13至3.58; p <0.001]。结论：本研究表明了GR_COPD计划对疾病特异性健康状况和恶化率的临床相关效果。建议实施针对急性加重治疗严重COPD的老年患者计划。

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