Pharmacoeconomics of Orphan Disease Treatment with a Focus on Hereditary Angioedema

William R. Lumry

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Pharmacoeconomics of Orphan Disease Treatment with a Focus on Hereditary Angioedema

机译：孤儿病治疗的药物经济学，重点在遗传性血统血统

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This article discusses orphan diseases, their prevalence, legislative incentives to encourage development of therapies, and the impact of treatment on health care payment systems. Specifically, the cost burden of hereditary angioedema on patients, health care systems, and society is reviewed. The impact of availability of and access to novel and specific therapies on morbidity, mortality, and overall burden of disease is explored. Changes in treatment paradigms to improve effect and reduce cost of treatment are presented.

机译：本文讨论了孤儿疾病，普遍存在的疾病，立法激励措施，以鼓励发展疗法，以及治疗对医疗保健支付系统的影响。具体而言，综述了患者，医疗保健系统和社会遗传性血统的成本负担。探讨了可用性和获取新的和特异性疗法对发病率，死亡率和疾病的总体负担的影响。提出了治疗范例的变化，以改善效果和降低治疗成本。

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来源
《Immunology and allergy clinics of North America》 |2017年第3期|共12页
作者
William R. Lumry;
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作者单位

Internal Medicine/Allergy/Immunology Division University of Texas Southwestern Medical School;

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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
Pharmacoeconomics; Orphan disease; Hereditary angioedema; Burden; Treatment;

机译：药物经济学;孤儿病;遗传性血统;负担;治疗;

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专利

1. Pharmacoeconomics of Orphan Disease Treatment with a Focus on Hereditary Angioedema [J] . William R. Lumry Immunology and allergy clinics of North America . 2017,第3期

机译：孤儿病治疗的药物经济学，重点在遗传性血统血统
2. Hereditary Angioedema: The Economics of Treatment of an Orphan Disease [J] . William Raymond Lumry Frontiers in Medicine . 2018,第6期

机译：遗传性血管性水肿：治疗孤儿疾病的经济学
3. Availability of and access to orphan drugs: an international comparison of pharmaceutical treatments for pulmonary arterial hypertension, Fabry disease, hereditary angioedema and chronic myeloid leukaemia. [J] . Blankart CR, Stargardt T, Schreyogg J PharmacoEconomics . 2011,第1期

机译：孤儿药物的可获得性和可获得性：肺动脉高压，法布里病，遗传性血管性水肿和慢性粒细胞白血病的药物治疗的国际比较。
4. FOCUS ON HEREDITARY DISEASES GENETIC PREDISPOSITIONS CLINICAL LABORATORY DIAGNOSTIC APPROACH TO HEREDITARY DISEASES [C] . anonymous American College of Veterinary Internal Medicine Forum . 2008

机译：专注于遗传性疾病与遗传易感性临床和实验室诊断方法对遗传性疾病
5. Screening of natural products for their effect on kallikrein-kinin system: Potential implications in the treatment of hereditary angioedema. [D] . Madkhali, Hassan Abdu. 2015

机译：筛选天然产物对激肽释放酶激肽系统的影响：遗传性血管性水肿治疗的潜在影响。
6. Hereditary Angioedema: The Economics of Treatment of an Orphan Disease [O] . William Raymond Lumry 2018

机译：遗传性血管性水肿：治疗孤儿疾病的经济学
7. PSY58 AVAILABILITY OF AND ACCESS TO ORPHAN DRUGS:AN INTERNATIONAL COMPARISON OF PHARMACEUTICAL TREATMENTS FOR PULMONARY ARTERIAL HYPERTENSION, FABRY DISEASE, HEREDITARY ANGIOEDEMA AND CHRONIC MYELOID LEUKEMIA [O] . Blankart CR, Stargardt T, Schreyögg J 2010

机译：PSY58鸦片药物的可获得性和可及性：肺动脉高压，FAB，疾病，遗传性血管性充血和慢性粒细胞白血病的药物治疗的国际比较

Pharmacoeconomics of Orphan Disease Treatment with a Focus on Hereditary Angioedema

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