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首页> 外文期刊>Immunology Letters >Cooperation of intrathymic T15 idiotype-bearing B and complementary T cells in ontogeny of natural Treg cells involved in establishment of T15 clonal dominance
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Cooperation of intrathymic T15 idiotype-bearing B and complementary T cells in ontogeny of natural Treg cells involved in establishment of T15 clonal dominance

机译:在建立T15克隆优势的天然Treg细胞中携带肿瘤内携带B和互补T细胞的合作

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摘要

The mechanisms for dominant T15 idiotype selection are not well understood, yet the significance of idiotypic regulation has been suggested. We proposed that to become dominant V regions of a given subset of B-1a cell must establish a functional idiotypic network with complementary T cells. Features required for the cells involved in immune network and steps preceding the establishment of clonal dominance are suggested.
机译:占主导地位T15独立型选择的机制尚不清楚,但已经提出了独一无二的规范的重要性。 我们提出要成为占P-1A细胞的给定的v区的主导V区域,必须建立具有互补T细胞的功能性独特网络。 提出了涉及在建立克隆支配的免疫网络和步骤中所涉及的细胞所需的特征。

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