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首页> 外文期刊>European journal of preventive cardiology >Screening young athletes for diseases at risk of sudden cardiac death: role of stress testing for ventricular arrhythmias
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Screening young athletes for diseases at risk of sudden cardiac death: role of stress testing for ventricular arrhythmias

机译:筛选患有突然心脏死亡风险的疾病的年轻运动员:心室心律失常的压力测试的作用

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Aims The athletic preparticipation evaluation (PPE) protocol proposed by the European Society of Cardiology includes history, physical examination and resting electrocardiogram (ECG). The aim of this study was to assess the results of adding constant-load ECG stress testing (EST) to the protocol for the evaluation of ventricular arrhythmias (VA) inducibility. Methods We evaluated a consecutive cohort of young athletes with history, physical examination, resting ECG and EST. Athletes with VA induced by EST underwent 24-hour 12-lead Holter monitoring and echocardiography. Cardiac magnetic resonance (CMR) was reserved for those with frequent, repetitive or exercise-worsened VA, and for athletes with echocardiographic abnormalities. Results Of 10,985 athletes (median age 15 years, 66% males), 451 (4.1%) had an abnormal history, physical examination or resting ECG and 31 (0.28%) were diagnosed with a cardiac disease and were at risk of sudden cardiac death. Among the remaining 10,534 athletes, VA at EST occurred in 524 (5.0%) and a previously missed at-risk condition was identified in 23 (0.22%); the most common (N = 10) was an echocardiographically silent non-ischaemic left-ventricular fibrosis evidenced by CMR. The addition of EST increased the diagnostic yield of PPE by 75% (from 0.28% to 0.49%) and decreased the positive predictive value by 20% (from 6.9% to 5.5%). During a 32 +/- 21 months follow-up, no cardiac arrests occurred among either eligible athletes or non-eligible athletes with cardiovascular disease. Conclusions The addition of exercise testing for the evaluation of VA inducibility to history, physical examination and ECG resulted in an increase of the diagnostic yield of PPE at the expense of an increase in false-positive findings.
机译:旨在欧洲心脏病学会提出的运动预备评估(PPE)协议包括历史,体检和休息心电图(ECG)。本研究的目的是评估将恒定载荷的ECG应力测试(EST)添加到室心律失常(VA)诱导性评估的方案中。方法我们评估了一系列具有历史,体检,休息ECG和EST的历史上的年轻运动员队列。 EST诱导的va的运动员接受了24小时12个引线举行监测和超声心动图。为具有频繁,重复或运动恶化的VA的人保留心脏磁共振(CMR),以及具有超声心动图异常的运动员。结果10,985名运动员(中位年龄15岁,66%的男性),451(4.1%)具有异常的历史,体检或休息ECG和31(0.28%)被诊断出心脏病,并且存在突然心脏病的风险。在剩下的10,534名运动员中,在524(5.0%)中发生VA,在23(0.22%)中确定了先前错过的风险状况;最常见的(n = 10)是CMR证明的超声心动图沉默的非缺血性左心室纤维化。添加EST将PPE的诊断产率提高了75%(从0.28%至0.49%),并将阳性预测值降低20%(从6.9%到5.5%)。在32 +/- 21个月内随访期间,符合条件的运动员或具有心血管疾病的非合格运动员之间没有发生心脏骤停。结论对历史,体检和心电图评估VA诱导性的运动检测产生了PPE的诊断产量,以牺牲伪阳性结果增加。

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