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Role of MDCT as an effective imaging tool in detection of complications amongst oncological patients in a tertiary care oncology institute

机译:MDCT作为一种有效的成像工具,在第三级护理肿瘤学院检测肿瘤学患者中并发症的有效成像工具

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Objectives The objectives of the study are to evaluate the role of multidetector computed tomography (MDCT), its sensitivity and specificity in recognizing the complications related to oncology, and its treatment in patients with known malignancies and to determine how clinician's diagnosis, diagnostic dilemma, and management decisions are affected by the results of computed tomography (CT) in a tertiary care oncology setup. Materials and methods A thorough retrospective search of the database of 1 year in the Department of Radiology was done at our tertiary oncology center, of patients who were diagnosed or suspected with complications associated with cancer. In addition, patients, in whom acute emergencies were detected by the MDCT, were also included as these were mostly part of the complications related to the malignancies. A total of 207 patients were included after excluding patients in whom the final diagnosis was uncertain or in patients who died before a definitive diagnosis was made. Clinical details were noted and compared with the CT diagnosis of the complication. Results Out of the 207 patients, majority of complications were related to cardiovascular system [22.2%]. Gastrointestinal malignancies constituted the next most common [20.7%], followed by genitourinary [17.8%], central nervous system [9.6%], and respiratory system complications [8.2%]. The musculoskeletal and head and neck complications were seen in 4.8% of the total patients. The iatrogenic complications and those complications arising due to chemotherapy or radiotherapy were separated constituting about 5.3% of the total number of patients in the study. CT showed a sensitivity of 96.4%, specificity of 66.6%, positive predictive value of 98.4%, and negative predictive value of 46.1% in detecting these complications. Overall, CT detected 96.6% of complications which were not suspected clinically and detected 83% of complications supporting the clinical suspicion. Conclusion MDCT plays an important role in detecting the complications associated with malignancies. It helps in definitive diagnosis of those complications which are clinically suspected and also in recognizing those complications which may not be apparent clinically and thus can change the management strategies. This is probably the first comprehensive study in the English literature evaluating and highlighting the role of MDCT in recognizing various complications in patients with known malignancies.
机译:目的该研究的目标是评估多种传感器计算机断层扫描(MDCT)的作用,其敏感性和特异性,以识别与肿瘤学相关的并发症,以及其在已知恶性肿瘤患者的治疗,并确定临床医生的诊断,诊断困境如何以及管理决策受第三级护理肿瘤系统中计算机断层扫描(CT)的影响。材料和方法在我们的第三次肿瘤学中心完成了一年内的1年数据库的彻底回顾性,诊断或怀疑与癌症相关的并发症。此外,患者,急性紧急情况被MDCT检测到,也包括这些主要是与恶性肿瘤相关的并发症的一部分。在排除最终诊断的患者中,共有207名患者纳入了未确定的患者,或者在在明确诊断之前死亡的患者。注意到临床细节,并与复杂性的CT诊断进行比较。结果在207名患者中,大多数并发症与心血管系统有关[22.2%]。胃肠道恶性肿瘤构成了下一个最常见的[20.7%],其次是泌尿生殖[17.8%],中枢神经系统[9.6%]和呼吸系统并发症[8.2%]。患者患者的4.8%以4.8%看到肌肉骨骼和头部并发症。来自化疗或放射疗法引起的对生理并发症的并发症分离,占研究中患者总数的约5.3%。 CT显示敏感性为96.4%,特异性为66.6%,阳性预测值98.4%,检测这些并发症的负面预测值为46.1%。总体而言,CT检测到96.6%的并发症,在临床上未怀疑并检测到83%的并发症支持临床怀疑。结论MDCT在检测与恶性肿瘤相关的并发症方面发挥着重要作用。它有助于对那些在临床疑似的那些并发症的明确诊断,并识别这些并发症,这些并发症可能在临床上不明显,因此可以改变管理策略。这可能是英语文学评估和突出MDCT在患有已知恶性肿瘤患者的各种并发症中的作用的第一综合研究。

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