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首页> 外文期刊>Experimental and therapeutic medicine >Feasibility of dual-low scheme combined with iterative reconstruction technique in acute cerebral infarction volume CT whole brain perfusion imaging
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Feasibility of dual-low scheme combined with iterative reconstruction technique in acute cerebral infarction volume CT whole brain perfusion imaging

机译：双低方案的可行性联合急性脑梗死体积的迭代重建技术CT全脑灌注成像

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摘要

The feasibility of application of low-concentration contrast agent and low tube voltage combined with iterative reconstruction in whole brain computed tomography perfusion (CTP) imaging of patients with acute cerebral infarction was investigated. Fifty-nine patients who underwent whole brain CTP examination and diagnosed with acute cerebral infarction from September 2014 to March 2016 were selected. Patients were randomly divided into groups A and B. There were 28 cases in group A [tube voltage, 100 kV; contrast agent, iohexol (350 mg I/ml), reconstructed by filtered back projection] and 31 cases in group B [tube voltage, 80 kV; contrast agent, iodixanol (270 mg I/ml), reconstructed by algebraic reconstruction technique]. The artery CT value, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), dose length product, effective dose (ED) of radiation and brain iodine intake of both groups were measured and statistically analyzed. Two physicians carried out kappa (kappa) analysis on the consistency of image quality evaluation. The difference in subjective image quality evaluation between the groups was tested by chi(2). The differences in CT value, SNR, CNR, CTP and CT angiography subjective image quality evaluation between both groups were not statistically significant (P>0.05); the diagnosis rate of the acute infarcts between the two groups was not significantly different; while the ED and iodine intake in group B (dual low-dose group) were lower than group A. In conclusion, combination of low tube voltage and iterative reconstruction technique, and application of low-concentration contrast agent (270 mg I/ml) in whole brain CTP examination reduced ED and iodine intake without compromising image quality, thereby reducing the risk of contrast-induced nephropathy.
机译：研究了低浓度造影剂和低管电压在急性脑梗死患者的全脑电层断层摄影灌注（CTP）成像中迭代重建的可行性进行了研究。从2014年9月到2016年9月到2016年3月，患有全脑CTP检查和患有急性脑梗死患者的五十九名患者。患者随机分为A和B组。[管电压，100kV;造影剂，碘己酮（350mg I / ml），通过过滤后投影重建，B组[管电压，80kV;造影剂，碘血糖（270mg I / ml），由代数重建技术重建。测量和统计分析了在两组的辐射和脑碘摄入量的辐射和脑碘摄入量的动脉CT值，信噪比（SNR），对比度噪声比（CNR），剂量长度产品，有效剂量（ED）。两位医生对图像质量评估的一致性进行了κ（κ）分析。通过CHI（2）测试组之间主观图像质量评估的差异。两组间CT值，SNR，CNR，CTP和CT血管造影主体图像质量评估的差异在统计学上没有统计学意义（P> 0.05）;两组之间的急性梗死的诊断率没有显着差异;虽然B组（双低剂量组）中的ED和碘摄入量低于A组。总之，低管电压和迭代重建技术的组合，以及低浓度造影剂的应用（270mg I / ml）在全脑CTP检查中，减少ED和碘摄入量而不损害图像质量，从而降低了对比引起的肾病的风险。

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