首页> 外文期刊>Experimental and clinical endocrinology and diabetes: Official journal, German Society of Endocrinology [and] German Diabetes Association >Evaluation of Epicardial Adipose Tissue in Patients of Type 2 Diabetes Mellitus by Echocardiography and its Correlation with Intimal Medial Thickness of Carotid Artery
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Evaluation of Epicardial Adipose Tissue in Patients of Type 2 Diabetes Mellitus by Echocardiography and its Correlation with Intimal Medial Thickness of Carotid Artery

机译:超声心动图患者2型糖尿病患者外膜脂肪组织的评价及其与颈动脉内侧厚度的相关性

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The present study aimed to evaluate the diagnostic value of echocardiography in measuring the thickness of epicardial adipose tissue (EAT) of the patients of type 2 diabetes mellitus (T2DM) and its correlation with the intimal-medial thickness of the carotid artery (cIMT) to investigate the relationship between EAT and cIMT. 68 patients of T2DM were enrolled and were divided into 2 groups: group of T2DM with duration 10 years (33 cases). And 30 healthy subjects were enrolled as the control group. The thickness of EAT and cIMT were measured by echocardiography and high-frequency ultrasonography. The thickness of EAT and IMT of the carotid artery of 2 type 2 diabetic groups (duration 10 years) were significantly higher than that of the control group (all p 10 years were significantly higher than that of the group of T2DM with duration <= 10 years (p < 0.05). In univariate analysis, the thickness of EAT was positively and significantly associated with age (r = 0.412, p < 0.05), BMI (r = 0.566, p < 0.05), waist circumference (r = 0.475, p < 0.05), LDL (r = 0.425, p < 0.05), TG (r = 0.496, p < 0.05), duration of diabetes (r = 0.384, p < 0.05) and cIMT (r = 0.456, p < 0.05). In multiple stepwise regression analyses, age, BMI and IMT of carotid artery were appeared to be significantly associated with EAT (p < 0.05 for all). In conclusion, routine screening of EAT and cIMT by ultrasonography in type 2 diabetic patients helps us to predict cardiovascular risks and prevent further development of cardiovascular complications.
机译:本研究旨在评估超声心动图在测量2型糖尿病患者(T2DM)的心外膜脂肪组织(EAT)的厚度及其与颈动脉(CIMT)的内膜厚度的相关性的诊断价值调查吃和CIMT之间的关系。 68例T2DM患者注册,分为2组:T2DM组,持续10年(33例)。和对照组一起注册了30个健康受试者。通过超声心动图和高频超声检查测量吃和CIMT的厚度。 2型糖尿病群(持续10年)的颈动脉的吃和IMT的厚度明显高于对照组(所有P 10年明显高于T2DM组的持续时间<= 10多年(P <0.05)。在单变量分析中,饮食的厚度是正且显着相关的(r = 0.412,p <0.05),bmi(r = 0.566,p <0.05),腰围(r = 0.475, P <0.05),LDL(r = 0.425,p <0.05),Tg(r = 0.496,p <0.05),糖尿病持续时间(r = 0.384,p <0.05)和cimt(r = 0.456,p <0.05) 。在多个阶下的回归分析中,颈动脉的年龄,BMI和IMT似乎与饮食有显着相关(所有P <0.05)。总之,2型糖尿病患者的超声检查常规筛选和CIMT有助于我们预测心血管风险,防止心血管并发症的进一步发展。

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