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Treatment strategies for hot flushes.

机译:热冲洗的治疗策略。

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BACKGROUND: Vasomotor symptoms are the most common complaints for which menopausal women seek medical care. Eighty per cent of all menopausal women will have hot flushes and night sweats, and of these 9% will have severe symptoms impacting their quality of life. Ideally, treatment should target the group most severely afflicted, and options for treatment should be tailored to each woman, since, for most women, vasomotor symptoms spontaneously resolve in 3 - 5 years. Recommendation at this time is for the shortest duration of therapy, which means that episodic review of therapy is indicated. OBJECTIVE: To review the latest literature investigating therapies for vasomotor symptoms and to discuss their effectiveness with emphasis on placebo-controlled, randomized clinical trials. METHODS: A literature search in PubMed for 'vasomotor symptoms', 'menopause symptoms', 'hot flushes', 'hot flashes' and 'night sweats' from 2003 to the present was performed. CONCLUSIONS: Estrogen remains the gold standard for treating vasomotor symptoms. As investigations into the physiology of hot flushes continue, centrally active drugs (selective serotonin or norepinephrine-serotonin reuptake inhibitors and gabapentin) have increased in use. The benefit from dietary herbal supplements is still inconclusive; however, recent studies have shown some mild response to soy and black cohosh.
机译:背景:血管运动症状是绝经妇女寻求医疗保健的最常见投诉。所有绝经妇女中有八十百分之九是热冲洗和盗汗,其中9%会有严重的症状影响他们的生活质量。理想情况下,治疗应该针对最严重的折磨,治疗方案应根据大多数女性量身定制治疗选择,因为大多数女性,血管传神症状在3 - 5年内自发地解决。此时的建议是为了获得最短的治疗持续时间,这意味着表明了治疗的情节综述。目的:审查最新文献调查血管运动症状的疗法,并讨论其强调安慰剂对照,随机临床试验的效果。方法:在PubMed中搜索'血管素症状','更年期症状','热冲洗','热闪烁','热闪光'和'夜汗'进行了2003年。结论:雌激素仍然是治疗血管运动症状的金标准。随着对热冲洗生理的调查继续,使用中央活性药物(选择性血清素或去甲肾上腺素 - 血清素再摄取抑制剂和加巴亨顿)在使用中增加。膳食草药补充剂的益处仍然不确定;然而,最近的研究表明对大豆和黑色Cohosh的一些温和的反应。

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