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首页> 外文期刊>Experimental Gerontology >Effects of aquatic exercise on insulin-like growth factor-1, brain-derived neurotrophic factor, vascular endothelial growth factor, and cognitive function in elderly women
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Effects of aquatic exercise on insulin-like growth factor-1, brain-derived neurotrophic factor, vascular endothelial growth factor, and cognitive function in elderly women

机译：水生运动对胰岛素样生长因子-1，脑源神经营养因子，血管内皮生长因子和认知功能的影响

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The purpose of this study was to investigate the effects of a 16-week aquatic exercise program on brain-derived neurotrophic factor (BDNF), insulin-like growth factor-1 (IGF-1), and vascular endothelial growth factor (VEGF) levels, as well as cognitive function in elderly women. The subjects were 20 elderly women aged 68-80 years, randomly divided into an aquatic exercise group (n = 10) and a control group (n = 10). The aquatic exercises were performed for 60 min, three times per week for 16 weeks, and the intensity was progressively increased every 4 weeks (40-50% of heart rate reserve (HRR) for weeks 1-4, 50-60% of HRR for weeks 5-8, 60-65% of HRR for weeks 9-12, and 65-70% of HRR for weeks 13-16). The data were analyzed using two-way repeated measures analysis of variance, paired t-test, and independent t-test with an alpha level to indicate significance set at.05 for all tests. After the 16-week aquatic exercise program, the BDNF and IGF-1 levels (p < .01, respectively), and cognitive function (p < .05) of the aquatic exercise group showed significant changes. BDNF, IGF-1, and cognitive function levels (p < .01, respectively) were significantly different between the aquatic exercise group and control group. The results of this study suggest that regular aquatic exercise in elderly women during the early stages of aging can increase the expression of BDNF and IGF-1, thus maintaining and improving cognitive function.
机译：本研究的目的是探讨16周的水生运动程对脑衍生的神经营养因子（BDNF），胰岛素样生长因子-1（IGF-1）和血管内皮生长因子（VEGF）水平的影响以及老年妇女的认知功能。受试者为68-80岁的20岁女性，随机分为水生锻炼组（n = 10）和对照组（n = 10）。水生锻炼进行了60分钟，每周三次进行16周，每4周逐渐增加（40-50％的心率储备（HRR），每周1-4，50-60％的人力资源周为5-8,60-65％的人力资源生产数周9-12，65-70％的人力资源3月13日至15日）。使用双向重复测量的方差，配对T检验和与α水平的独立t检验进行分析数据，以表示所有测试的05次设置的重要性。在16周的水生锻炼计划之后，水生运动组的BDNF和IGF-1水平（分别为P <.01）和认知功能（P <.05）显示出显着变化。 BDNF，IGF-1和认知函数水平（分别为P <.01）在水生锻炼组和对照组之间显着差异。本研究的结果表明，老化早期阶段的老年妇女的正常水生运动可以增加BDNF和IGF-1的表达，从而维持和改善认知功能。

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