Transplant chimerism in porcine structural vascularized bone allotransplants

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Transplant chimerism in porcine structural vascularized bone allotransplants

机译：猪结构血管化骨分征植物中的移植斜切性

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Background: Bone allotransplant viability can be maintained long-term by implanting arteriovenous (AV) bundles and creating an autogenous neoangiogenic circulation. Only short-term immunosuppression is required. This study investigates the origin of viable osteocytes observed in areas of active bone remodeling in orthotopically transplanted tibiae in a Yucatan mini-pig model.

机译：背景：通过植入动静脉（AV）束并产生自生新致原循环，可以长期维持骨同质性活力。只需要短期免疫抑制。本研究调查在尤卡坦迷你猪模型中在原位移植的胫骨上的活性骨质重塑区域观察到的活性骨细胞的起源。

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《Gene: An International Journal Focusing on Gene Cloning and Gene Structure and Function》 |2020年第2020期|共7页
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正文语种 eng
中图分类医学遗传学;
关键词
Vascularized Composite Allotransplantation (VCA); Surgical angiogenesis; Repopulation;

机译：血管化复合异种持续物（VCA）;外科血管生成;重新灌注;

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专利

1. Transplant chimerism in porcine structural vascularized bone allotransplants [J] . Gene: An International Journal Focusing on Gene Cloning and Gene Structure and Function . 2020,第期

机译：猪结构血管化骨分征植物中的移植斜切性
2. VASCULARIZED BONE TRANSPLANT CHIMERISM MEDIATED BY VASCULAR ENDOTHELIAL GROWTH FACTOR [J] . Willems Wouter F., Larsen Mikko, Friedrich Patricia F., Microsurgery. . 2015,第1期

机译：血管内皮生长因子介导的血管化骨移植嵌合体
3. Tolerance induced by bone marrow chimerism prevents transplant vascular sclerosis in a rat model of small bowel transplant chronic rejection. [J] . Orloff SL, Yin Q, Corless CL, Transplantation: Official Journal of the Transplantation Society . 2000,第7期

机译：在小肠移植慢性排斥反应的大鼠模型中，骨髓嵌合体诱导的耐受性可防止移植血管硬化。
4. Vascularized bone marrow transplantation leads to higher levels of hematopoietic chimerism than conventional cellular bone marrow transplantation [C] . Zamfirescu D, Popovicu C, Bularda A, World Society for Reconstructive Microsurgery . 2011

机译：血管化的骨髓移植导致比常规细胞骨髓移植更高水平的造血逆变
5. Nuclease-Based Editing in the Porcine Genome: A Strategy to Facilitate Porcine-to Human Xenotransplantation [D] . Butler, James R. 2017

机译：猪基因组中基于核酸酶的编辑：促进猪到人异种移植的策略。
6. Combined treatment with regulatory T cells and vascularized bone marrow transplantation creates mixed chimerism and induces donor-specific tolerance to vascularized composite allografts without cytoreductive conditioning [O] . Jeng-Yee Lin, Feng-Chou Tsai, Christopher Glenn Wallace, 2013

机译：结合调节性T细胞和血管化骨髓移植的治疗可产生混合嵌合现象并诱导供体对血管化复合同种异体移植物的特异性耐受而无需进行细胞还原性调节
7. Combined treatment with regulatory T cells and vascularized bone marrow transplantation creates mixed chimerism and induces donor-specific tolerance to vascularized composite allografts without cytoreductive conditioning [O] . Lin, J-Y, Tsai, F-C, Wallace, Christopher G, 2013

机译：与调节性T细胞和血管化骨髓移植的联合治疗产生混合嵌合体并诱导供体特异性对血管化复合同种异体移植物的耐受性而无需细胞减灭条件化

Transplant chimerism in porcine structural vascularized bone allotransplants

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