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Endoscopic features and clinical outcomes of colorectal mucosa-associated lymphoid tissue lymphoma

机译:结肠直肠粘膜相关淋巴组织淋巴瘤的内窥镜特征和临床结果

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摘要

Background and Aims Colorectal mucosa-associated lymphoid tissue (MALT) lymphoma is a rare disease. The purpose of this study was to investigate the clinical and endoscopic features of colorectal MALT lymphoma. Methods Patients diagnosed with colorectal MALT lymphoma at Asan Medical Center from 2002 to 2016 were eligible. Medical records were reviewed to investigate clinical features and treatment outcomes. Endoscopic pictures were assessed to characterize the endoscopic features of colorectal MALT lymphoma. Results A total of 51 patients were enrolled. The median age was 60 years (interquartile range, 55-71), and 21 (41%) were men. Twenty-six patients (51%) were asymptomatic. Forty-four patients (86%) were in early disease stages, namely Lugano stages I, II, and II E . Endoscopic appearances were classified as 4 distinct types: subepithelial tumor type (26 patients, 51%), polyposis type (10 patients, 20%), epithelial mass type (7 patients, 14%), and ileitis type (8 patients, 16%). The rectum (20 patients, 39%) was the most common location, followed by the ileocecal area (15 patients, 30%). An initial endoscopic impression of lymphoma was made in only 7 patients. Forceps biopsy sampling as the initial tissue acquisition method could histologically diagnose MALT lymphoma in 28 of 35?patients (80%). Polypectomy as the initial histologic diagnosis could diagnose MALT lymphoma in 16 of 16 patients. Progression-free and overall survival rates at 5 years were 92% and 94%, respectively. Conclusions Colorectal MALT lymphomas show various endoscopic appearances, complicating the endoscopic?suspicion of colorectal MALT lymphoma. The prognosis of colorectal MALT lymphoma was excellent.
机译:背景和AIMS结直肠粘膜相关淋巴组织(麦芽)淋巴瘤是一种罕见的疾病。本研究的目的是探讨结直肠麦芽淋巴瘤的临床和内窥镜特征。方法从2002年到2016年诊断为Asan Medical Center患有结肠直肠麦芽淋巴瘤的患者符合条件。审查了医疗记录以调查临床特征和治疗结果。评估内窥镜图像以表征结直肠麦芽淋巴瘤的内窥镜特征。结果共有51名患者。中位年龄为60岁(四分位数,55-71),21(41%)是男性。二十六名患者(51%)无症状。四十四名患者(86%)在早期疾病阶段,即卢加诺阶段I,II和II e。内窥镜外观被归类为4个不同类型:映像肿瘤型(26例,51%),息肉型(10名患者,20%),上皮质量型(7例,14%)和对炎型(8例,患者,16% )。直肠(20名患者,39%)是最常见的位置,其次是对联区域(15名患者,30%)。仅在7名患者中进行了淋巴瘤的初始内窥镜印象。钳子活检采样作为初始组织采集方法可以组织学上诊断麦芽淋巴瘤在35中的28例(80%)(80%)。作为初始组织学诊断的多药切除术可以在16名患者中诊断麦芽淋巴瘤。 5年的无进展和整体生存率分别为92%和94%。结论结直肠麦芽淋巴瘤显示各种内窥镜外观,使内窥镜术后复杂于结直肠麦芽淋巴瘤。结直肠麦芽淋巴瘤的预后优异。

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  • 来源
    《Gastrointestinal Endoscopy》 |2018年第2期|共11页
  • 作者单位

    Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine;

    Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine;

    Department of Pathology Asan Medical Center University of Ulsan College of Medicine;

    Department of Pathology Asan Medical Center University of Ulsan College of Medicine;

    Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine;

    Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine;

    Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine;

    Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine;

    Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine;

    Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine;

    Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine;

    Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 消化系及腹部疾病;
  • 关键词

  • 入库时间 2022-08-20 03:04:13

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