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首页> 外文期刊>European Journal of Obstetrics, Gynecology and Reproductive Biology: An International Journal >Endometriosis in adolescence: Early manifestation of the traditional disease or a unique variant?
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Endometriosis in adolescence: Early manifestation of the traditional disease or a unique variant?

机译：青春期的子宫内膜异位症：传统疾病的早期表现还是独特的变种？

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Little is known about Endometriosis in Adolescents and its prevalence is yet to be estimated. Traditional Endometriosis seems to be, by far, quite different with this unique variant when it comes to clinical presentation, management and course of the disease. Further research needs to be conducted in order to classify these two, phenomenically similar, diseases. Adolescents with a history of dysmenorrhea and chronic pelvic pain (CPP) imply findings suggestive of endometriosis. The severity of the disease is variable, from superficial endometriosis to deep endometriotic lesions or even ovarian endometriomas. The course of the disease also suggests the necessity of a more personalized approach since among adolescents, endometriosis could resolve or even aggravate with no particular pathophysiological pattern. Some studies suggest that appropriate treatment should be based on the understanding of the pathophysiologic mechanisms. Long term course of the disease, as well as, a high recurrence rate pose a difficulty to scientists, deciding conservative over operative surgery. Some believe that early operation on superficial forms of endometriosis could potentially prevent deep endometriotic lesions in the long-run. Others find medication such as, combined oral contraceptive pills (COCPs), progestins, levonorgestrel intrauterine device or gonadotrophin releasing hormone analogues (GnRHa), more appropriate for this age group. Last but not least, operation with post-operative hormonal treatment remains the most common treatment approach. Nevertheless, our limited understanding of the disease, as well as, particular factors needed to be taken into consideration, for instance, bone formation in this age group, underline the necessity of further studies, needed to be appointed, in order to determine the best diagnostic and therapeutic approach. (c) 2020 Elsevier B.V. All rights reserved.
机译：对青少年的子宫内膜异位症知之甚少，尚未估计其普遍存在。当涉及临床展示，管理和疾病过程时，传统的子宫内膜异位症似乎是与这种独特的变种相当不同。需要进行进一步的研究，以便对这两种，象征性相似，疾病进行分类。具有痛经历史的青少年和慢性骨盆疼痛（CPP）意味着调查结果表明子宫内膜异位症。这种疾病的严重程度是可变的，从浅表子宫内膜异位症到深内膜病变病变甚至卵巢子宫内膜瘤。该疾病的过程还表明，由于青少年，子宫内膜异位症可以解决或甚至没有特定的病理生理学模式来解决更个性化方法的必要性。一些研究表明，适当的治疗应该是基于对病理生理机制的理解。疾病的长期过程，以及高复发率为科学家造成了难度，决定保守的手术手术。有些人认为，浅表形式的子宫内膜异位症的早期操作可能会在长期的情况下防止深度内静脉曲位病变。其他人发现药物，如口服避孕药（COCPS），孕激素，左旋血糖肠道装置或促性婴儿药释放激素类似物（GNRHA），更适合于该年龄组。最后但并非最不重要的是，术后荷尔蒙治疗的操作仍然是最常见的治疗方法。尽管如此，我们对疾病的有限理解，以及需要考虑的特殊因素，例如，在该年龄组中骨骼形成，强调进一步研究的必要性，以便确定最佳诊断和治疗方法。 （c）2020 Elsevier B.V.保留所有权利。

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