...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>General hospital psychiatry >Exercise effects on depression: Possible neural mechanisms
【24h】

Exercise effects on depression: Possible neural mechanisms

机译：对抑郁症的运动效果：可能的神经机制

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Abstract Depression is a syndrome of stress- and emotion-dysregulation, involving compromised structural integrity of frontal-limbic networks. Meta-analytic evidence indicates that volumetric reductions in the hippocampus, anterior cingulate cortex, prefrontal cortex, striatum, and amygdala, as well as compromised white matter integrity are frequently observed in depressed adults. Exercise has shown promise as an effective treatment for depression, but few studies have attempted to characterize or identify the neural mechanisms of these effects. In this review, we examined the overlap between structural brain abnormalities in depression and the effects of exercise on brain structure in adults, to highlight possible neural mechanisms that may mediate the positive effects of exercise on depressive symptoms. The prefrontal cortex, anterior cingulate cortex, hippocampus, and corpus callosum emerged as structural neural markers that may serve as targets for exercise-based treatments for depression. These findings highlight the need for randomized exercise interventions to test these proposed neurobiological mechanisms of exercise on depression.
机译：摘要抑郁症是压力和情感 - 失调的综合症，涉及损害额肢体网络的结构完整性。荟萃分析证据表明，在抑制成年人中经常观察到海马，前刺型皮质，前梗塞，前序列，粒子和杏仁菌的体积减少，以及受损的白质完整性。练习表明了承诺作为抑郁症的有效治疗，但很少有研究试图表征或识别这些效果的神经机制。在本综述中，我们研究了抑郁症结构脑异常之间的重叠和运动对成人脑结构的影响，突出了可能介导运动对抑郁症状的积极影响的可能性机制。前额叶皮质，前刺刺肌，海马和胼call病变被呈现为结构神经标记物，其可以作为抑郁型锻炼治疗的靶标。这些发现突出了对随机运动干预的需要，以测试这些提出的抑郁运动的神经生物学机制。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号