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首页> 外文期刊>Evidence-based complementary and alternative medicine: eCAM >A Meta-Analysis of Randomized Controlled Trials of Yiqi Yangyin Huoxue Method in Treating Diabetic Nephropathy
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A Meta-Analysis of Randomized Controlled Trials of Yiqi Yangyin Huoxue Method in Treating Diabetic Nephropathy

机译：益气阳素Huoxue方法在治疗糖尿病肾病中的荟萃分析

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摘要

Objective. The purpose of this systematic review is to evaluate the evidence of Yiqi Yangyin Huoxue Method for diabetic nephropathy. Methods. 11 electronic databases, through September 2015, were searched to identify randomized controlled trials of Yiqi Yangyin Huoxue Method for diabetic nephropathy. The quality of the included trials was assessed using the Jadad scale. Results. 26 randomized controlled trials were included in our review. Of all the included trials, most of them were considered as high quality. The aggregated results suggested that Yiqi Yangyin Huoxue Method is beneficial to diabetic nephropathy in bringing down the microalbuminuria (SMD = -0.98, 95% CI -1.22 to -0.74), serum creatinine (SMD = -0.56, 95% CI -0.93 to -0.20), beta-2 microglobulin (MD = 0.06, 95% CI 0.01 to 0.12), fasting plasma glucose (MD = -0.35, 95% CI -0.62 to -0.08), and 2-hour postprandial blood glucose (MD = 1.13, 95% CI 0.07 to 2.20), but not in decreasing blood urea nitrogen (SMD= -0.72, 95% CI -1.47 to 0.02) or 2-hour postprandial blood glucose (SMD = -0.48, 95% CI -1.01 to 0.04). Conclusions. Yiqi Yangyin Huoxue Method should be a valid complementary and alternative therapy in the management of diabetic nephropathy, especially in improving UAER, serum creatinine, fasting blood glucose, and beta-2 microglobulin. However, more studies with long follow-up are warrant to confirm the current findings.
机译：客观的。该系统审查的目的是评估益气杨小宁Huoxue方法对糖尿病肾病的证据。方法。 11名电子数据库，截至2015年9月，旨在识别益气杨小宁Huoxue方法的随机对照试验糖尿病肾病。使用JADAD规模评估包括试验的质量。结果。我们的审查中包含26项随机对照试验。在所有包括的试验中，大多数被认为是高质量的。汇总结果表明，益气阳素肺嘴法对糖尿病肾病有益，使微蛋白尿（SMD = -0.98,95％CI -1.22至-0.74），血清肌酐（SMD = -0.56,95％CI -0.93至 - 0.20），β-2微球蛋白（MD = 0.06,95％CI 0.01至0.12），禁食血浆葡萄糖（MD = -0.35,95％CI -0.62至-0.08）和2小时的餐后血糖（MD = 1.13 ，95％CI 0.07至2.20），但不降低血尿尿素氮（SMD = -0.72,95％CI -1.47至0.02）或2小时后血糖（SMD = -0.48,95％CI -1.01至0.04 ）。结论。益气阳阴Huoxue方法应该是糖尿病肾病的管理中有效的互补和替代治疗，尤其是改善UAER，血清肌酐，空腹血糖和β-2微胶质蛋白。但是，在长期后续的情况下，更多的研究是确认当前调查结果。

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    Ou Jiao Ying; Huang Di; Wu Yan Sheng; Xu Lin; He Fei; Wang Hui Ling; Shi Li Qiang; Wan Qiang; He Li Qun; Gao Jian Dong;

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    Shanghai Univ Tradit Chinese Med Shuguang Hosp Dept Nephrol 528 Zhang Heng Rd Shanghai 201203;

    Shanghai Univ Tradit Chinese Med Shuguang Hosp Dept Nephrol 528 Zhang Heng Rd Shanghai 201203;

    Shanghai Univ Tradit Chinese Med Shuguang Hosp Dept Nephrol 528 Zhang Heng Rd Shanghai 201203;

    Shanghai Univ Tradit Chinese Med Shuguang Hosp Dept Nephrol 528 Zhang Heng Rd Shanghai 201203;

    Shanghai Univ Tradit Chinese Med Shuguang Hosp Dept Nephrol 528 Zhang Heng Rd Shanghai 201203;

    Shanghai Univ Tradit Chinese Med Shuguang Hosp Dept Nephrol 528 Zhang Heng Rd Shanghai 201203;

    Shanghai Univ Tradit Chinese Med Shuguang Hosp Dept Nephrol 528 Zhang Heng Rd Shanghai 201203;

    Shanghai Univ Tradit Chinese Med Shuguang Hosp Dept Nephrol 528 Zhang Heng Rd Shanghai 201203;

    Shanghai Univ Tradit Chinese Med Shuguang Hosp Dept Nephrol 528 Zhang Heng Rd Shanghai 201203;

    Shanghai Univ Tradit Chinese Med Shuguang Hosp Dept Nephrol 528 Zhang Heng Rd Shanghai 201203;

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  • 中图分类 临床医学;
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