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首页> 外文期刊>European addiction research >Synthetic Cannabinoid Use in a Psychiatric Patient Population: A Pilot Study
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Synthetic Cannabinoid Use in a Psychiatric Patient Population: A Pilot Study

机译：在精神病患者人口中使用合成大麻素：试点研究

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Background: Consumption of natural cannabis (NC) and synthetic cannabinoids (SCs) has been associated with psychotic disorders. We compared the prevalence of use, consumer profiles, and psychosis-inducing potential of NC and SCs in a specific high-risk population. Methods: This prospective pilot study included 332 patients (18-64 years, mean 36.83, SD 13.33). Patients' sociodemographics and medical histories as well as illicit substance use and psychiatric symptom histories were collected using a drug consumption survey that assessed the use of new psychoactive substances and the Psychotic Symptoms Interview. Results: In total, 7.2% of all patients, 10.6% of psychotic patients, and 4.5% of nonpsychotic patients reported SC consumption. Compared with SCs, NC was consumed much more frequently by its users (mean 222.73, SD 498.27). NC and SC use induced persistent psychosis. Psychotic symptoms were first experienced by patients with a history of NC or SC use during intoxication and persisted after cessation (> 1 year) of drug use. Positive and negative symptoms tended to be more severe in SC and NC users, respectively. Conclusions: NC and SCs may cause different symptom clusters. These relationships should be further evaluated. (C) 2017 S. Karger AG, Basel
机译：背景：自然大麻（NC）和合成大麻素（SCS）的消耗与精神病疾病有关。我们比较了NC和SCS在特定高风险人群中的使用流行，消费者曲线和精神病诱导潜力。方法：该前瞻性试验研究包括332名患者（18-64岁，平均36.83，SD 13.33）。使用药物消费调查，收集患者的社会碘目和医疗历史以及非法物质使用和精神症状历史，评估了新的精神活性物质和精神病症状访谈。结果：总共7.2％的患者，10.6％的精神病患者，4.5％的非患者报告SC消费。与SCS相比，NC由其用户频繁消耗（平均222.73，SD 498.27）。 NC和SC使用诱导持续的精神病。患者首次经历了精神病症状，患者患有NC或SC在中毒过程中使用的患者，并在戒毒（> 1年）后持续存在。 SC和NC用户分别趋于严重的正面和阴性症状。结论：NC和SCS可能导致不同的症状簇。应进一步评估这些关系。 （c）2017年S. Karger AG，巴塞尔

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