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Comparison of body composition and physical and cognitive function between older Japanese adults with no diabetes, prediabetes and diabetes: A cross‐sectional study in community‐dwelling Japanese older people

机译:旧日本成年人的身体成分和身体和认知功能的比较,没有糖尿病,前驱糖尿病和糖尿病:社区住宅日本老年人的横截面研究

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Aim Diabetes is associated with not only cardiovascular and cerebrovascular disease, but also reductions in physical and cognitive function. The purpose of the present study was to determine whether muscle strength, walking ability and balance declined in Japanese community‐dwelling older adults with diabetes or prediabetes. Methods We analyzed data from comprehensive health checkups carried out for 1689 individuals (710 men, 979 women; mean age 71.4?±?5.6?years) between 2011 and 2016. Participants were divided into three groups: no diabetes (non‐history of diabetes and glycated hemoglobin level 5.7%), prediabetes (non‐history of diabetes, but glycated hemoglobin level was 5.7–6.4%) and diabetes (history of diabetes or glycated hemoglobin level 6.4%). Physical and cognitive function were compared between groups after adjusting for covariates. Results Participants with diabetes showed higher levels of obesity, comorbidity, gonarthrosis, and body fat, and lower levels of physical function relative to those observed in participants with prediabetes or no diabetes. After adjusting covariates, participants with diabetes showed significantly lower grip strength ( P ??0.010), slower walking speed ( P ??0.005), longer Timed Up and Go test time ( P ??0.007) and less time spent standing on one foot ( P ??0.001) relative to those with no diabetes, but not those with prediabetes. Conclusions Significant functional decline was observed in community‐dwelling older adults with diabetes, but not in those with prediabetes. Prevention of the progression of prediabetes to diabetes is important in avoiding reductions in physical function. Geriatr Gerontol Int 2018; 18: 1031–1037 .
机译:目标糖尿病不仅与心血管和脑血管疾病有关,而且还与身体和认知功能降低。本研究的目的是确定肌肉力量,行走能力和平衡是否在日本社区居住的老年人患有糖尿病或前驱糖尿病。方法分析了1689人(710名男子,979名妇女的综合健康检查中的数据)2011年和2016年之间的综合健康检查和糖化血红蛋白水平& 5.7%),前奶酪(糖尿病的非历史,但糖尿病血红蛋白水平为5.7-6.4%)和糖尿病(糖尿病史或糖化血红蛋白水平& 6.4%)。在调整协变量后,在组之间比较了物理和认知功能。结果糖尿病的参与者显示出更高水平的肥胖,合并症,吞咽病和体脂肪,以及相对于参与者观察到的糖尿病或没有糖尿病的人的身体功能较低。调整协变量后,糖尿病的参与者显着降低抓握强度(P≤0.010),步行速度较慢(p≤≤0.005),更长的时间上升并去测试时间(p≤≤0.007)和更少相对于没有糖尿病的那些,每花一只脚站立(p?0.001),但不是患有前奶油的人。结论社区住宅老年人患有糖尿病的大型成年人,但不在患有Prediabetes的人群中观察到显着的功能下降。预防前脂肪的前进进程对糖尿病对避免身体功能的减少是重要的。 GeriaTr Gerontol int 2018; 18:1031-1037。

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