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首页> 外文期刊>Graefe's archive for clinical and experimental ophthalmology: Albrecht von Graefes Archiv fur klinische und experimentelle Opthalmologie >Characteristic appearances of fundus autofluorescence in treatment-naive and active polypoidal choroidal vasculopathy: a retrospective study of 170 patients
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Characteristic appearances of fundus autofluorescence in treatment-naive and active polypoidal choroidal vasculopathy: a retrospective study of 170 patients

机译：治疗 - 天真和活性息肉脉络膜病变的眼底自发荧光的特征外观：170例患者的回顾性研究

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Purpose To investigate the characteristic appearances of fundus autofluorescence (FAF) in patients with treatment-naive and active polypoidal choroidal vasculopathy (PCV). Method Cases with the diagnosis of treatment-naive and active PCV from November 2012 to May 2017 at Peking Union Medical College Hospital were retrospectively reviewed. All patients underwent comprehensive ophthalmologic examination. Autofluorescence (AF) findings were described at the retinal sites of the corresponding lesions identified and diagnosed using indocyanine green angiography and spectral-domain optical coherence tomography. Results One hundred seventy patients with 192 affected eyes were included. The logMAR BCVA of the patients were 0.53?±?0.28. The six AF patterns of 243 polypoidal lesions were confluent hypo-AF with hyper-AF ring (49.8%), confluent hypo-AF (22.6%), hyper-AF with hypo-AF ring (3.7%), granular hypo-AF (7.0%), blocked hypo-AF due to hemorrhage (8.6%), and polyps without apparent AF changes (8.2%). For 146 branching vascular networks (BVNs), 97.3% were granular hypo-AF, and others were blocked hypo-AF due to hemorrhage. Conclusion In eyes with treatment-naive and active PCV, the polypoidal lesions and BVNs induce characteristic FAF changes. FAF images provide reliable adjunct reference for the diagnosis of PCV.
机译：目的探讨治疗 - 幼稚和活性息肉脉络膜血管病变（PCV）患者眼底自发荧光（FAF）的特征外观。追溯审查，于2012年11月至2017年11月诊断治疗天真和活跃的PCV的方法病例被回顾性审查。所有患者均接受综合眼科检查。在使用吲哚菁绿色血管造影和光谱 - 域光学相干断层扫描鉴定和诊断的相应病变的视网膜位点描述自发荧光（AF）发现。结果包括192名受影响的眼睛的一百七十患者。患者的Logmar BCVA为0.53？±0.28。 243个息肉病变的六种AF模式是融合的Hypo-AF，具有Hyper-AF环（49.8％），汇合的Hypo-AF（22.6％），Hypo-AF环（3.7％），颗粒式Hypo-AF（ 7.0％），由于出血（8.6％）而被阻塞的Hypo-AF，以及没有明显的AF变化的息肉（8.2％）。对于146个分枝血管网络（BVN），97.3％是粒状的Hypo-AF，其他因出血引起的Hypo-AF被阻断。结论在治疗幼稚和活性PCV的眼中，息肉病变和BVN诱导特征FAF变化。 FAF图像为PCV的诊断提供可靠的辅助参考。

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