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首页> 外文期刊>BJOG: an international journal of obstetrics and gynaecology >Factors affecting adequacy of Pipelle and Tao Brush endometrial sampling.
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Factors affecting adequacy of Pipelle and Tao Brush endometrial sampling.

机译：影响Pipelle和Tao Brush子宫内膜采样充分性的因素。

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OBJECTIVE: To compare factors influencing adequacy of endometrial samples obtained using two outpatient sampling devices--Pipelle and Tao Brush. DESIGN: Pragmatic unblinded trial with investigation schedule randomised separately within two groups according to endometrial cancer risk. SETTING: Gynaecology outpatient clinic of a large city hospital in Edinburgh, Scotland. POPULATION: All women referred to a gynaecology outpatient clinic during a 28-month period complaining of abnormal vaginal bleeding. METHODS: Women were assigned to two 'risk groups' for endometrial cancer ('high risk' for postmenopausal women and 'moderate risk' for premenopausal women aged over 40 years or with other risk factors). Women in each risk group had both types of biopsy and were randomised to two outpatient visualisations: hysteroscopy and/or transvaginal ultrasound scan. MAIN OUTCOME MEASURES: Completion of the investigation, adequacy of sample and acceptability of investigation to women. RESULTS: In 200 high-risk women, adequate samples were significantly more likely to be obtained by Tao Brush than Pipelle (P < 0.001). Nulliparity was strongly associated with failed insertion for both devices (P < 0.001). Inadequate samples were strongly associated with postmenopausal status only for Pipelle (P < 0.001), and among premenopausal women, for both samplers, with nulliparity (P < 0.001). A significantly greater proportion of women preferred the Tao Brush to the Pipelle endometrial sampler (P < 0.001). CONCLUSIONS: In postmenopausal women, Tao Brush sampling offers advantages over use of Pipelle, and the former should be considered as an alternative or additional sampling device in this group of women.
机译：目的：比较影响使用两种门诊采样设备（Pipelle和Tao Brush）获得的子宫内膜样本的适当性的因素。设计：实用的无盲试验，研究计划根据子宫内膜癌的风险随机分为两组。地点：苏格兰爱丁堡一家大型城市医院的妇科门诊。人口：所有妇女在28个月内转诊至妇科门诊，抱怨阴道异常出血。方法：将女性子宫内膜癌分为两个“风险组”（绝经后妇女为“高风险”，而40岁以上或具有其他风险因素的绝经前妇女为“中度风险”）。每个风险组中的妇女都有两种活检类型，并随机分为两种门诊可视化：宫腔镜检查和/或经阴道超声扫描。主要观察指标：完成调查，抽样是否足够，对妇女的接受程度。结果：在200名高危女性中，陶刷获得的样本明显高于Pipelle（P <0.001）。对于两个设备，失败均与插入失败密切相关（P <0.001）。样本不足的样本仅与Pipelle的绝经后状态密切相关（P <0.001），而绝经前的女性中两个样本的样本均与产前无关联（P <0.001）。较大比例的女性更倾向于使用陶刷而不是Pipelle子宫内膜采样器（P <0.001）。结论：在绝经后的妇女中，陶笔法采样比使用Pipelle更具优势，在这组女性中，前者应被视为替代或额外的采样装置。

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