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首页> 外文期刊>Gynecological endocrinology: the official journal of the International Society of Gynecological Endocrinology >Risk factors, fractures, and management of pregnancy-associated osteoporosis: a retrospective study of 14 Turkish patients
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Risk factors, fractures, and management of pregnancy-associated osteoporosis: a retrospective study of 14 Turkish patients

机译：妊娠相关骨质疏松症的危险因素，骨折和管理：14例土耳其患者的回顾性研究

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摘要

Pregnancy-associated osteoporosis (PAO) is a rare but painful disease. The current study aimed to investigate the demographic and clinical features, risk factors, treatment options, and outcomes of Turkish patients with PAO. In our retrospective, cross-sectional, and descriptive study the time to PAO diagnosis was 3.6 months. Pain and loss of height were detected in 78.6% and 28.6% of patients, respectively. As such, 60.6% of patients reported fractures at the thoracic area, 30.3% at the lumbar area, and 9.1% at the sacral area. While 14.3% of patients had optimal vitamin D status during pregnancy, 64.3% had vitamin D deficiency, and 21.4% had vitamin D insufficiency. Of the patients, 21.4% received anticoagulant therapy during their pregnancy. Dual X-ray absorptiometry scans revealed that osteoporosis was predominantly in the trabecular bone (L1-L4 Z-score -2.9, Femur Z score -2.19). Management options included supplements of calcium with vitamin D (93%), weaning the baby (79%), specific treatments for osteoporosis (64%), use of a supportive corset (50%), and exercise (21%), respectively. In addition, after delivery, 35.7% of patients were administered denosumab, 21.4% bisphosphonate, and 7.1% were given teriparatide. Data of the clinical features, treatments, and outcomes of PAO may contribute to early detection and management.
机译：妊娠相关骨质疏松症（PAO）是一种罕见但痛苦的疾病。目前的研究旨在调查土耳其患者的人口统计学和临床​​特征，危险因素，治疗方案和去除患者的PAO患者的结果。在我们的回顾性，横断面和描述性研究中，PAO诊断的时间为3.6个月。 78.6％和28.6％的患者分别检测到高度疼痛和损失。因此，60.6％的患者报告了胸部区域的骨折，腰部区域30.3％，骶骨区域9.1％。虽然14.3％的患者在怀孕期间具有最佳的维生素D状态，但64.3％的维生素D缺乏症，21.4％具有维生素D功能不全。在患者的患者中，21.4％在怀孕期间接受抗凝血治疗。双X射线吸收测量扫描显示，骨质疏松症主要在小梁骨中（L1-L4 Z-Score -2.9，股骨Z得分-2.19）。管理选择包括钙的补充剂，维生素D（93％），婴儿断奶（79％），骨质疏松症的特定治疗（64％），分别使用支撑紧身胸衣（50％）和运动（21％）。此外，在递送后，35.7％的患者被施用Denosumab，21.4％双膦酸盐，7.1％得到萜状水。 PAO的临床特征，治疗和结果的数据可能有助于早期检测和管理。

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