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首页> 外文期刊>Gynecological endocrinology: the official journal of the International Society of Gynecological Endocrinology >Effect of pre-gestational weight and gestational weight gain in women with gestational diabetes controlled with medication on pregnancy outcomes - is recommended weight gain too liberal?
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Effect of pre-gestational weight and gestational weight gain in women with gestational diabetes controlled with medication on pregnancy outcomes - is recommended weight gain too liberal?

机译：妊娠期糖尿病患者孕妇前妊娠重量和妊娠重量增益的影响 - 建议体重增加过于自由

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摘要

This is a retrospective cohort study of women with GDM treated with glucose-lowering agents that were followed and gave birth between 2005 and 2015 in the Assaf Harofeh medical center, Israel. Classification and regression tree method identified four groups according to adverse outcomes, consisted of 74 women with pre-gestational BMI below 25, 98 women with BMI 25-31, 90 women 31-39 and 18 women above 39. Respectively, median GWG was 12 kg (8-16), 11kg (8-15), 7.5 kg (3.75-11) and 5 kg (-1.5 to 11.5) (p< .001). The risk for composite adverse outcomes was higher in the groups of BMI 25-31 (73.5%) and 31-39 (83.3%) in comparison to BMI < 25 (51.4%) and 39< (55.6%), p< .001. In women with pre-gestational BMI of < 25, GWG of more than the median resulted in odds ratio of 2.75 (1.07-7.08, p = .036) for adverse pregnancy outcomes compared with participants who gained less than the median. Maternal obesity is related to adverse pregnancy outcomes. Women with GDM with normal pre-gestational BMI who gained weight according to IOM recommendations still experienced adverse outcomes.
机译：这是一种回顾性队列队列，伴有葡萄糖降低剂量治疗的女性，在ASSAF Harofeh医疗中心在2005年至2015年之间进行了，以色列。分类和回归树种方法根据不利结果确定了四组，其中包括74名孕妇前夹住性BMI 25分，98名妇女BMI 25-31，90例女性31-39名和18名上方39名。分别为12岁，中位数GWG为12 KG（8-16），11kg（8-15），7.5千克（3.75-11）和5千克（-1.5至11.5）（P <.001）。与BMI <25（51.4％）和39（55.6％），P <0.001，BMI 25-31（73.5％）和31-39组（73.5％）和31-39（83.3％）组中复合不良结果的风险较高（83.3％） 。在患有预妊娠的孕态BMI的女性中超过中学的GWG，导致不利妊娠结果的赔率比为2.75（1.07-7.08，p = .036）。与少于中位数的参与者相比，与参与者相比。母亲肥胖与不良妊娠结果有关。具有GDM的妇女，具有正常的夹住性BMI，根据IOM建议获得重量的重量仍然经历过不利的结果。

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